Sökning: "heme proteins"

Visar resultat 16 - 20 av 56 avhandlingar innehållade orden heme proteins.

  1. 16. Kinetics of proton and electron transfer in heme-copper oxidases

    Författare :Peter Lachmann; Pia Ädelroth; Örjan Hansson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heme-copper oxidase; electron transfer; proton transfer; nitric oxide reductase; ba3 oxidase; flow-flash; laser-flash photolysis; Biochemistry; biokemi;

    Sammanfattning : Heme-copper oxidases are transmembrane proteins that are found in aerobic and anaerobic respiratory chains. During aerobic respiration, these enzymes reduce dioxygen to water. The energy released in the reaction is used to transport protons across a biological membrane. LÄS MER

  3. 17. Production of human heme-binding proteins in plants for potential pharmaceutical and nutritional uses

    Författare :Magnus Carlsson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Plants have a long history as a source of nutrition and medication. In the last few decades, interest has also emerged in using plants as a production system for protein pharmaceuticals, in part due to possible scale-up- and safety-benefits with this method of production. LÄS MER

  4. 18. Assembly and Function of Nitric Oxide Reductase from Paracoccus denitrificans

    Författare :Maximilian Kahle; Pia Ädelroth; Hans-Georg Koch; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; non-heme iron; cofactor; heme-copper oxidase; AAA ; cNOR; chaperone; metal ion insertion; MoxR; nor accessory genes; FeB; liposomes; membrane mimetics; nanodiscs; reconstitution; enzymatic mechanism; NO reduction; O2 reduction; Biochemistry; biokemi;

    Sammanfattning : Bacterial denitrification is a part of the global nitrogen cycle and comprises the stepwise reduction of nitrate to molecular nitrogen, which is released to the atmosphere. Cytochrome c-dependent nitric oxide reductase (cNOR) from Paracoccus (P.) denitrificans catalyzes the reduction of nitric oxide to nitrous oxide and water. LÄS MER

  5. 19. On new and current treatments for Diamond-Blackfan anemia

    Författare :Sara Sjögren; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :Diamond-Blackfan anemia; Erythropoiesis; Ribosome biogenesis; Heme synthesis; Glucocorticoids; p53; Globin translation; HRI; a1-microglobulin;

    Sammanfattning : Diamond-Blackfan anemia (DBA) is a rare congenital disease where the patients suffer from macrocytic anemia due to reduced numbers of erythroid precursors in the bone marrow. Most patients carry mutations in ribosomal proteins, such as ribosomal protein S19 (RPS19), which causes deficient ribosome biogenesis and affects protein translation. LÄS MER

  7. 20. Catalytic and Structural Properties of Heme-containing Fatty Acid Dioxygenases : Similarities of Fungal Dioxygenases and Cyclooxygenases

    Författare :Ulrike Garscha; Ernst Oliw; Per-Johan Jakobsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dioxygenase; prostaglandin H synthase; Gaeumannomyces graminis; Aspergilli; hydroperoxide isomerase; linoleate diol synthase; cytochrome P450; oxylipin; Pharmaceutical pharmacology; Farmaceutisk farmakologi; Farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : 7,8-Linoleate diol synthase (7,8-LDS) of the take-all pathogen of wheat, Gaeumannomyces graminis, converts linoleic acid to 8R-hydroperoxyoctadecadienoic acid (8-HPODE) by 8-dioxygenase activity (8-DOX), and further isomerizes the hydroperoxide to 7S,8S-dihydroxyoctadecadienoic acid (7,8-DiHODE) by hydroperoxide isomerase activity. Sequence alignment showed homology to prostaglandin H synthase (PGHS), and both enzymes share structural and catalytic properties. LÄS MER