Sökning: "hassan"

Visar resultat 1 - 5 av 91 avhandlingar innehållade ordet hassan.

  1. 1. Methods for Preclinical Evaluation of Cytotoxic Drugs : With Special Reference to the Cyanoguanidine CHS 828 and Hollow Fiber Method

    Författare :Saadia Bashir Hassan; Elin Lindhagen; Rolf Larsson; Mats O Karlsson; Mustapha Hassan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; CHS 828; in vitro; in vivo; hollow fiber; models; NF-kB; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : The novel cyanoguanidine CHS 828 has shown promising antitumor activity in many in vitro and in vivo studies. The long-term 14 days in vitro hollow fiber cultures, where tumor cells from different tumor cell lines were cultured inside semipermeable fibers, were more resistant to CHS 828 and other cytotoxic drugs than the shorter-term 3 days cultures. LÄS MER

  3. 2. Novel glycomimetic inhibitors and proteolysis-targeting chimeras for human galectins

    Författare :Mujtaba Hassan; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Galectins; Galectin-3; Galectin-8; benzimidazole; affinity; selectivity; X-ray; PROTAC;

    Sammanfattning : Galectins are a family of soluble proteins that bind β-D-galactopyranoside-containing glycoconjugates through their conserved carbohydrate-recognition domains. Galectins have emerged as promising drug targets due to their involvement in various pathological conditions, such as tumor growth and metastasis, autoimmune and inflammatory diseases, as well as metabolic disorders. LÄS MER

  4. 3. Late Surgical Complications of Roux-en-Y Gastric Bypass

    Författare :Hassan Zaigham; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bariatric Surgery; Bariatric Surgery adverse effects; Gastric Bypass; Gastric Bypass adverse effects; Internal herniation; Intussusception; Choledocholithiasis; Endoscopic retrograde cholangiopancreatography; Surgical Complications; Surgical adverse effects; Small bowel obstruction; Laparoscopy;

    Sammanfattning : .... LÄS MER

  5. 4. Essays on Systemic Risk in European Banking

    Författare :Hassan Sabzevari; Nationalekonomiska institutionen; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Systemic Risk; CoVaR; GIIPS; Quantile Regression; DCC; CDS;

    Sammanfattning : This thesis makes a contribution to systemic risk literature in the European banking system. The intimate interdependence between the European banking industries and the fragile GIIPS debt market has jeopardized the banking sector in Europe. LÄS MER

  7. 5. Multiomics strategy in clinical immunology aiding unsolved antibody deficiencies

    Författare :Hassan Abolhassani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Clinical and immunological phenotyping of a cohort of consecutive dysgammaglobulinemic patients with unknown genetic defects underwent genomic (e.g. whole-exome sequencing) and other relative multiomics (e.g. LÄS MER