Sökning: "glomerular disease"

Visar resultat 6 - 10 av 121 avhandlingar innehållade orden glomerular disease.

  1. 6. Immunoglobulin A nephropathy and disease complications : register-based studies

    Författare :Simon Jarrick; Jonas Ludvigsson; Sigrid Lundberg; Adina Symreng; Colin C. Geddes; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunoglobulin A nephropathy; nephrology; validation studies; register studies; cohort studies; mortality; ischemic heart disease; pregnancy; preterm birth;

    Sammanfattning : Immunoglobulin A nephropathy (IgAN) is the commonest primary glomerular disease worldwide. A kidney biopsy is required for the diagnosis. IgA immune-complex depositions sets off a cascade leading to renal scarring, proteinuria and hypertension. LÄS MER

  3. 7. Functional and molecular aspects of the glomerular barrier

    Författare :Anna Björnson Granqvist; Göteborgs universitet; []
    Nyckelord :glomerular endothelium; glycocalyx; podocyte; proteoglycan; glycosaminoglycans; nephrotic syndrome;

    Sammanfattning : The kidneys are crucial for maintaining a normal salt-water balance in the body, which is a prerequisite for life. They do that by filtering 180 liters of plasma per day across the highly permselective glomerular barrier and reabsorbing 99 % of the filtrate. LÄS MER

  4. 8. The role of glycoproteins in glomerular pathophysiology

    Författare :Alina Khramova; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteoglycans; Extracellular matrix; IgA nephropathy; Diabetic kidney disease;

    Sammanfattning : Chronic kidney disease (CKD) is increasing worldwide and has a prevalence of around 10%. With time patients are at risk of losing their renal function and will need dialysis or transplantation for survival. There are no specific treatments available and mechanisms behind the onset and progression of CKD are still not fully investigated. LÄS MER

  5. 9. Intrarenal oxygen homeostasis in acute and chronic kidney disease

    Författare :Oskar Nensén; Fredrik Palm; Börje Haraldsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; acute kidney injury; oxygen; kidney disease; renal physiology; Fysiologi; Physiology;

    Sammanfattning : Renal hypoxia has been recognized as a common feature of acute and chronic kidney injury arising from varying etiologies. It has also been proposed to provide a driving mechanism for the transition from acute to chronic kidney disease (CKD). LÄS MER

  7. 10. Characterization of novel glomerular proteins : role in physiology and disease

    Författare :Ann-Charlotte Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy. The costs for treatment of CKD represent an enormous burden to the health care system. LÄS MER