Sökning: "genotoxicity"

Visar resultat 26 - 30 av 36 avhandlingar innehållade ordet genotoxicity.

  1. 26. Towards improved drinking water safety : the use of in vitro bioassays to optimize treatment processes and assess chemical hazards

    Författare :Maria Yu; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Drinking water safety has been primarily dependent on the monitoring of only a limited number of individual chemicals via chemical analysis, which is insufficient to characterize the myriad of hazardous chemicals present in water. Effect-based methods (EBMs) using in vitro bioassays are useful in that they evaluate biological effects from all the known and unknown chemicals in the water and draw on toxicological principles. LÄS MER

  3. 27. Comparative studies of alkylating and N-heterocyclic compounds on different genetic endpoints with special emphasis on amplification of minisatellite sequences

    Författare :Eva Agurell; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Several mutational events are involved in the multistage process of cancer. Genetic instability of tumor DNA is shown in a variety of genetic changes such as point mutations, chromosomal aberrations, aneuploidy, DNA amplification and somatic recombination. LÄS MER

  4. 28. Towards New Generation of Hemoglobin-Based Blood Substitutes

    Författare :Sandeep Chakane; Tillämpad biokemi; []
    Nyckelord :hemoglobin; Fetal hemoglobin; Hemoglobin-based oxygen carrier; DNA cleavage; comet assay;

    Sammanfattning : Blood transfusion is a clinically significant and crucial process, which saves millions of lives every year. However,shortage of donated blood and the risk of virus transmission through transfusible blood seriously affect theavailability of the blood. LÄS MER

  5. 29. Molecular genetic alterations in chemically-induced lymphomas

    Författare :Shi-Mei Zhuang; V. Peter Collins; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Lymphoma is one of the most common malignancies in humans. Its incidence has increased rapidly in the past 30 years. However, the molecular mechanisms underlying the development of lymphomas are largely unknown.Environmental carcinogens play an important role in tumorigenesis. LÄS MER

  7. 30. Arsenic exposure and early biomarkers of cardiovascular disease and cancer

    Författare :Syeda Shegufta Ameer; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :Cardiovascular disease; DNA methylation; Telomere length; MtDNAcn; Gene expression; Cancer;

    Sammanfattning : AbstractInorganic arsenic exposure through drinking water is a serious public health concern because of its association to cancer and non-cancer diseases. More than one hundred million people world-wide are exposed to elevated levels of arsenic on a regular basis. LÄS MER