Sökning: "epithelial ovarian cancer EOC"

Visar resultat 6 - 10 av 16 avhandlingar innehållade orden epithelial ovarian cancer EOC.

1. 6. Early Diagnosis of Epithelial Ovarian Cancer - Analysis of Novel Biomarkers

   Författare :Björg Kristjansdottir; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epithelial Ovarian Cancer; Ovarian cyst fluid; Tumor biomarkers; Proteomics; Pelvic mass; Mass Spectometry; SELDI-TOF MS; iTRAQ;

   Sammanfattning : Early Diagnosis of Epithelial Ovarian Cancer - Analysis of Novel Biomarkers Björg Kristjánsdóttir Department of Obstetrics & Gynecology, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Sweden ABSTRACT Background: Majority of epithelial ovarian cancer (EOC) is detected in advanced stage with bad prognosis and high mortality. Reliable diagnostic markers are lacking, pre-cancerous lesions in the more aggressive tumors are not clearly defined, vague or unspecific early symptoms, and the localization of the ovaries, deep in the pelvis contributes to late diagnose. LÄS MER

3. 7. Clinical implementation of novel diagnostic biomarkers for epithelial ovarian cancer - Can we improve diagnosis?

   Författare :Maria Lycke; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian neoplasms; EOC; Diagnosis; protein biomarkers; HE4; CA125; Algorithms; RMI; ROMA; NGS; rare mutations; liquid biopsies; screening;

   Sammanfattning : Background: Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer. The 5-year survival is about 30%, a consequence of failure to establish early diagnosis due to unspecific symptoms. LÄS MER

4. 8. Hormone concentrations during pregnancy and maternal risk of epithelial ovarian cancer

   Författare :Helena Schock; Eva Lundin; Annika Idahl; Renée Turzanski Fortner; Anne Zeleniuch-Jacquotte; Shelley S Tworoger; Umeå universitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; epithelial ovarian cancer; sex steroid hormones; IGF-I; placental GH; AMH; pregnancy; prospective study; patologi; Pathology;

   Sammanfattning : Background: The aim of this thesis was to study the relationship of pre-diagnostic circulating concentrations of sex steroid hormones (androgens, estradiol, 17-hydroxyprogesterone, and progesterone), growth factors (insulin-like growth factor-I (IGF-I), placental growth hormone (GH)), sex hormone binding globulin (SHBG), and anti-Müllerian hormone (AMH) with risk of epithelial ovarian cancer (EOC) overall, and by tumor invasiveness and histology. A longitudinal study was used to assess patterns of hormonal changes during a single pregnancy, and in two consecutive pregnancies. LÄS MER

5. 9. Cancer Evolution under Chemotherapy Treatment

   Författare :Kaname Uno; Cancercellers evolution; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; Wilms tumor; chemotherapy resistance; ascites; spheroids; diffuse anaplasia;

   Sammanfattning : Background: Chemotherapy resistance is a critical issue in oncology, being responsible for the majority of deaths in modern cancer care. My PhD work has focused on two cancer types where such drug resistance is a major clinical issue: epithelial ovarian cancer (EOC) and Wilms tumor (WT). LÄS MER

7. 10. Predictive and prognostic factors of epithelial ovarian cancer and pseudomyxoma peritonei

   Författare :Kathrine Bjersand; Inger Sundström Poromaa; Pernilla Dahm Kähler; Uppsala universitet; []
   Nyckelord :;

   Sammanfattning : The overall aim of my thesis was to investigate potential prognostic and predictive factors associated with the tumor cells of epithelial ovarian cancer (EOC) and the gastrointestinal tumor pseudomyxoma peritonei (PMP) to improve and individualize cancer therapy. Both PMP and EOC can develop into peritoneal carcinomatosis (PC), which is characterized by widespread metastasis of cancer tumors in the peritoneal cavity. LÄS MER