Sökning: "epithelial ovarian cancer EOC"
Visar resultat 11 - 15 av 16 avhandlingar innehållade orden epithelial ovarian cancer EOC.
11. Tumor progression in the ovary and colon. The interaction of Wnt-signaling, transcription and formation of prostaglandins
Sammanfattning : Alterations in cell-cell adhesion, intracellular signaling and transcriptional regulation are common events during transformation of cells to the malignant phenotype. Different cellular defense mechanisms, e.g. inflammatory responses, mediated by prostaglandins, have also been associated with tumor development. LÄS MER
12. Molecular steps towards improving prognosis in ovarian cancer
Sammanfattning : Epithelial ovarian cancer (EOC) is the most lethal of gynecological cancers, and cure rates have improved very little in the last 30 years. The most common histological subtypes are serous, endometrioid, clear cell and mucinous EOC. To date, all EOC have been treated as one entity. LÄS MER
13. Fertility-sparing surgery in young women with ovarian cancer and borderline ovarian tumors
Sammanfattning : Background: Based on the cell origin of the tumor, ovarian cancer (OC) is divided in epithelial ovarian cancer (EOC), including borderline ovarian tumors (BOT), and nonepithelial ovarian cancer (NEOC), which includes sex cord stromal tumors and malignant ovarian germ cell tumors. Each subgroup contains several histological subtypes of varying malignant potential and prognosis. LÄS MER
14. Molecular signatures of progression and chemoresistance in epithelial ovarian carcinoma
Sammanfattning : Epithelial ovarian carcinoma (EOC) is a heterogeneous disease generally classified into five histopathological subtypes; low- and high-grade serous, endometrioid, clear cell and mucinous carcinomas. Although each subtype has distinct clinical and molecular characteristics, they are all treated with surgery and platinum/ taxane chemotherapy. LÄS MER
15. An epidemiologic study of epithelial ovarian malignancies : with a focus on hormone-related factors
Sammanfattning : The main purpose of this thesis was to examine estrogen and progestin effects of hormone replacement therapy, in relation to the risk for epithelial ovarian neoplasias. Other intentions were to assess reproductive factors, oral contraceptive use, previous gynecologic surgeries, and family history of ovarian cancer according to the risk of ovarian neoplasias, and to connect these findings to different hypotheses regarding ovarian carcinogenesis. LÄS MER