Sökning: "ependymal cells"

Visar resultat 16 - 20 av 22 avhandlingar innehållade orden ependymal cells.

  1. 16. Experimental spinal cord injury : development of protection and repair strategies in rats

    Författare :Matthias Erschbamer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Spinal cord injury typically results in neurological deficits that can not be reversed, often leaving patients bound to a wheelchair. Current treatment strategies are not very successful. Despite many promising experimental strategies, clinical translation has so far been very limited. LÄS MER

  3. 17. Megalin, an Endocytotic Receptor with Signalling Potential

    Författare :Mårten Larsson; Lars Rask; Bo Åkerström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Megalin; LRP-2; Postsynaptic density-95; Retinol-binding protein; Oligodendrocytes; Central nervous system; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Megalin is an endocytotic receptor belonging to the low-density lipoprotein family. It has often been viewed only as merely a scavenger receptor of absorptive and secretory epithelia. Recent work has revealed that the megalin intracellular domain contains several motifs potentially binding proteins involved in signal transduction. LÄS MER

  4. 18. Studies of presenilin function in neurodegeneration and in human embryonic CNS during development

    Författare :Beata Kostyszyn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Presenilin-1 (PS1) and -2 (PS2) gene mutations cause early onset familial Alzheimer's disease (FAD). Presenilins provide gamma-secretase activity for cleaving transmembrane proteins such as the amyloid precursor protein (APP), Notch receptors and ligands. LÄS MER

  5. 19. Physiological roles of amyloid precursor protein in vivo - zebrafish as a model

    Författare :Jasmine Chebli; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid-beta precursor protein; amyloid precursor protein-b; zebrafish; physiological functions; development; trigeminal ganglia; ependyma; cilia; proteomics; translational adaptation;

    Sammanfattning : Amyloid-beta precursor protein (APP) is an evolutionarily conserved transmembrane protein expressed in many different tissues. APP belongs to a gene family consisting of two other APP-like proteins (APLP1 and APLP2). LÄS MER

  7. 20. Anatomical studies of the dopamine system in the hypothalamus and the pituitary gland

    Författare :Arash Hellysaz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The hypothalamus is a small, evolutionarily conserved brain region, necessary for our survival as individuals and as a species. It collects various sensory inputs, process them to maintain homeostasis and to overcome stressors, and generates outputs that affect the autonomic nervous system, the endocrine system and somatomotor behaviors. LÄS MER