Sökning: "dienyl"

Hittade 4 avhandlingar innehållade ordet dienyl.

1. 1. Iron Carbonyl Mediated Parallel Synthesis

   Författare :Henrik Gradén; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dienyl; scavenger; solid phase; galectin inhibitor; oseltamivir; iron carbonyl complex; polymer bound reagent; cation; linker; parallel synthesis; active ester;

   Sammanfattning : This thesis describes the examination and development of cationic iron carbonyl complexes for use in parallel synthesis both in solution phase and on solid phase. A solution phase methodology for carbon-carbon and carbon-heteroatom formation, utilizing polymer bound reagents and scavengers and amenable for automation has been successfully developed. LÄS MER

3. 2. METAL CARBONYL MEDIATED REACTIONS - APPLICATIONS IN THE SYNTHESIS OF POTENTIAL GALECTIN INHIBITORS

   Författare :Nuria Parera Pera; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : AbstractThis work reports the development of an asymmetric version of the Nicholas reaction using monodentate phosphoramidites as ligands, which enables asymmetric synthesis from racemic starting material. In addition, we describe the application of metal carbonyl mediated reactions, such as the Pauson-Khand reaction (PKR) and reactions involving cationic iron carbonyl dienyl complexes, for the synthesis of potential galectin inhibitors, implicated in human inflammatory responses and various pathologies. LÄS MER

4. 3. Derivatising Carbohydrates for Biological Applications

   Författare :Anders Bergh; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Carbohydrates have a wide variety of functions in Nature. The somewhat old view of carbohydrates only functioning as building blocks or energy sources, has been overturned by the newer insight that carbohydrates are deeply involved in recognition processes, such as receptors for bacteria, viruses, antibodies and proteins. LÄS MER

5. 4. Transition Metal-Mediated Selective Functionalizations of Bio-Derived Building Blocks

   Författare :Petter Dunås; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phenols; Heck reaction; microbial arene oxidation; green chemistry; domino reactions; chirality transfer; palladium; metal carbonyl; azulenes; renewable resources; iron;

   Sammanfattning : In order to transition to a more sustainable chemical industry, it is necessary to replace the fossil starting materials that are largely used today with renewable ones. Starting materials available from abundant natural sources, or which can be efficiently produced via a biotransformation, are of high interest in this regard. LÄS MER