Sökning: "dSTORM"

Hittade 2 avhandlingar innehållade ordet dSTORM.

1. 1. Roles of unconventional ion channels and insulin granule structure in the pathogenesis of type-2 diabetes

   Författare :Mohammad Barghouth; Diabetes - öpatofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T2D; pancreatic islets; mechanosensitive channels; Piezo1; beta-cell specific Piezo1 knockout mouse; KATP channel; dSTORM; Piezo1; Cav3.2; AQP1; SD; RRP; Insulin secretion and action;

   Sammanfattning : T2D is the most widespread endocrine disease. In conventional stimulus secretion coupling increased blood glucose is metabolized causing an increased intracellular level of ATP and closure of the KATP channels, and this, in turn, depolarizes the cell membrane leading to the opening of voltage-gated Ca2+ channels, the influx of Ca2+ and exocytosis of insulin granules. LÄS MER

3. 2. Studies on the plasticity of glutamate receptors and its role for neuronal calcium homeostasis

   Författare :Linda Westin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Calcium is the most important and versatile signaling molecule in the brain. Neurons are equipped with a variety of tools to utilize this simple ion in diverse ways. From controlling the millisecond fast neurotransmitter release, to reshaping neuronal structure and function. LÄS MER