Sökning: "cystic fibrosis transmembrane conductance regulator"

Visar resultat 16 - 20 av 20 avhandlingar innehållade orden cystic fibrosis transmembrane conductance regulator.

1. 16. Studies of Tight Junctions and Airway Surface Liquid in Airway Epithelium with Relevance to Cystic Fibrosis

   Författare :Harriet Nilsson; Godfried M Roomans; Anca Dragomir; Marie Johannesson; Olafur Baldurson; Uppsala universitet; []
   Nyckelord :;

   Sammanfattning : Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, due to a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is a cAMP-regulated Cl-channel involved in various regulatory processes. LÄS MER

3. 17. Studies as a basis for a possible introduction of newborn screening for cystic fibrosis in Sweden

   Författare :Isabelle de Monestrol; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disease in Caucasians. It is a multi-organ disease that results from mutations in the gene that encodes the CF transmembrane conductance regulator (CFTR) protein, which regulates ion transport at epithelial surfaces. LÄS MER

4. 18. Genetic and molecular determinants in inflammatory bowel disease

   Författare :Francesca Bresso; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Inflammatory Bowel Disease, IBD, are polygenic disorders that present itself to the clinician as a sum of interacting events arising from multiple factors of genetic, immunological and environmental origin, resulting in a chronic relapsing inflammation that manifests itself in two major forms, ulcerative colitis (UC) and Crohn Ls disease (CD). Shortage of reliable biomarkers for correct diagnosis and thus appropriate treatment regime is still a major problem for the clinically active physician. LÄS MER

5. 19. Host-microbe interactions in coxsackievirus infection : focus on innate immunity

   Författare :Michael Hühn; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Coxsackievirus group B (CVB) is a common virus that usually causes only mild symptoms in humans. However, occasionally these infections result in severe diseases like meningitis, myocarditis and pancreatitis. LÄS MER

7. 20. FtsH protease and ClpG disaggregase confer fitness advantages to the worldwide prevalent Pseudomonas aeruginosa clone C

   Författare :Shady Mansour Kamal; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Pseudomonas aeruginosa is an environmental bacterium and a frequent nosocomial pathogen causing a wide range of opportunistic infections, especially in immunocompromised patients. Clone C is one of the most prevalent groups of closely related strains distributed worldwide in the environment, such as in natural aquatic habitats, and the clinical settings, such as in patients with an underlying functional impairment of the cystic fibrosis transmembrane conductance regulator. LÄS MER