Sökning: "cullberg"

Hittade 5 avhandlingar innehållade ordet cullberg.

  1. 1. Direct Thrombin Inhibitors in Treatment and Prevention of Venous Thromboembolism: Dose – Concentration – Response Relationships

    Författare :Marie Cullberg; Mats O. Karlsson; Ulf G. Eriksson; Nick H.G. Holford; Uppsala universitet; []
    Nyckelord :Pharmaceutical biosciences; Ximelagatran; pharmacokinetic; pharmacodynamic; activated partial thromboplastin time; utility function; dosing strategy; venous thromboembolism; NONMEM; Farmaceutisk biovetenskap;

    Sammanfattning : For prevention and treatment of thrombotic diseases with an anticoagulant drug it is important that an adequate dose is given to avoid occurrence or recurrence of thrombosis, without increasing the risk of bleeding and other adverse events to unacceptable levels. The aim of this thesis was to develop mathematical models that describe the dose-concentration (pharmacokinetic) and concentration-response (pharmacodynamic) relationships of direct thrombin inhibitors, in order to estimate optimal dosages for treatment and long-term secondary prevention of venous thromboembolism (VTE). LÄS MER

  3. 2. On the role of HMGB1 and resistin in severe sepsis and septic shock

    Författare :Jonas Sundén-Cullberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Severe sepsis and septic shock are serious manifestations of infectious diseases. Mortality ranges from over 30 % in severe sepsis up to 60% in septic shock. Early antibiotic treatment and intensive care are mainstays of therapy, but outside of this, new treatments have only marginally improved survival. LÄS MER

  4. 3. SLPI and soluble BTLA as immunological markers in severe bacterial infections

    Författare :Anna Lange; Olof Hultgren; Jonas Sundén-Cullberg; Peter Bergman; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SLPI; sBTLA; sepsis; bloodstream infection; pneumonia;

    Sammanfattning : Clinical presentation, and outcome of infections are affected by host-, and etiology- (focus of infection and pathogen) related factors. The immune response is controlled by a network of regulating pathways. LÄS MER

  5. 4. Birgit Cullbergs Fröken Julie : en svensk balettklassiker

    Författare :Erik Näslund; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Cullberg; Birgit; 1908-1999; Fröken Julie; Balett; Koreografi; Dansare; Sverige; 1900-talet;

    Sammanfattning : Since Its creation ln 1950, Birgit Cullberg's ballet ”Miss Julie” has not only become a ballet classic In Sweden but has also become an Integral part of the International ballet repertory with few rivals in terms of popularity, productions and performances among ballets created after 1945. This dissertation discusses the place of the ballet in the choreographer’s development and In the general context of ballet at the time of its creation. LÄS MER

  7. 5. "Det var en plågsam stund, en stund af indre smärta" : En psykobiografi över Lina Sandells sorgebearbetning mellan åren 1858-1861

    Författare :Sofie Walter; Centrum för teologi och religionsvetenskap; []
    Nyckelord :HUMANIORA; HUMANITIES; religious coping; evangelical piety; religious attachment; forced grief; shame; Psychology;

    Sammanfattning : Bereavement and sorrow are complex phenomena and processes of the human psyche. Central to this doctoral thesis is Lina Sandell (1832–1903,one of Sweden’s most productive and prominent authors of evangelicalism during the 19th century. Her hymn texts ”Day by day” and ”Children of the Heavenly Father” are well known outside Scandinavia. LÄS MER