Sökning: "bloodstream infection"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden bloodstream infection.

  1. 1. Quantitative detection of bacterial DNA in whole blood in bloodstream infection

    Detta är en avhandling från Örebro : Örebro University

    Författare :Ingrid Ziegler; Örebro universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bloodstream infection; bacteremia; sepsis; DNA load; quantitative PCR; droplet digital PCR; 16S rDNA;

    Sammanfattning : This thesis aims to increase the knowledge on how quantitative PCR can be used in the diagnostics of bloodstream infections, with an emphasis on quantitative elements.In Papers I and II, we evaluated quantitative data from two commercial PCR tests for pathogen detection directly in blood, Magicplex Sepsis (I) and SeptiFast (II), from patients with suspected sepsis. LÄS MER

  2. 2. A holistic approach to host-pathogen interactions : Detecting the large to unravel the small

    Detta är en avhandling från Department of Immunotechnology, Lund University

    Författare :Kristoffer Sjöholm; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2017-05-04]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectromery; Proteomics; Host-pathogen interactions; Sepsis;

    Sammanfattning : Sepsis is one of the leading causes of mortality and morbidity in the world, and is an overreaction by the immune system due to pathogen invasion of the bloodstream. The interactions, particularly the protein interactions, between the host and pathogen are fundamental for the outcome of the disease. LÄS MER

  3. 3. Platelets and their immunomodulatory roles during Streptococcus pyogenes infection

    Detta är en avhandling från Division of Infection Medicine

    Författare :Sinead Hurley; Lunds universitet.; Lund University.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Sepsis and invasive bacterial infection is a major cause of human disease and death worldwide. Streptococcus pyogenes is one of the major pathogens responsible for bacterial infections, which range from mild to severe and life threatening conditions. S. LÄS MER

  4. 4. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis

    Detta är en avhandling från Örebro : Örebro University

    Författare :Sara Cajander; Örebro universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocyte HLA-DR; sepsis; immunosuppression; bloodstream infection; HLA-DRA; CIITA; qRT-PCR;

    Sammanfattning : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. LÄS MER

  5. 5. Coagulase-negative staphylococci in hematological malignancy

    Detta är en avhandling från Örebro : Örebro universitet

    Författare :Erik Ahlstrand; Örebro universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coagulase-negative staphylococci; hematological malignancy; Staphylococcus epidermidis; healthcare-associated infection; antibiotic susceptibility; molecular epidemiology; bloddstream infection; bacteremia; Medicin; Medicine;

    Sammanfattning : Bacterial infections are common in hematological malignancy. Coagulase-negative staphylococci (CoNS) are among the most prevalent causes of bacteremia in patients with hematological malignancies. LÄS MER