Sökning: "bloodstream infection"
Visar resultat 1 - 5 av 32 avhandlingar innehållade orden bloodstream infection.
1. Quantitative detection of bacterial DNA in whole blood in bloodstream infection
Sammanfattning : This thesis aims to increase the knowledge on how quantitative PCR can be used in the diagnostics of bloodstream infections, with an emphasis on quantitative elements.In Papers I and II, we evaluated quantitative data from two commercial PCR tests for pathogen detection directly in blood, Magicplex Sepsis (I) and SeptiFast (II), from patients with suspected sepsis. LÄS MER
2. Clinical Impact of Bloodstream Infections – Characterization, Risk factors and Outcome
Sammanfattning : Bloodstream infection (blood poisoning) and antibiotic resistance are increasing worldwide, and already cause the loss of millions of human lives each year. According to the World Health Organisation (WHO), bloodstream infections (BSIs) represent 20% of global mortality on a par with cardiac infarct, stroke, and major trauma. LÄS MER
3. Improved diagnosis and management of sepsis and bloodstream infection
Sammanfattning : Sepsis is a severe organ dysfunction triggered by infections, and a leading cause of hospitalization and death. Concurrent bloodstream infection (BSI) is common and around one third of sepsis patients have positive blood cultures. LÄS MER
4. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis
Sammanfattning : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. LÄS MER
5. SLPI and soluble BTLA as immunological markers in severe bacterial infections
Sammanfattning : Clinical presentation, and outcome of infections are affected by host-, and etiology- (focus of infection and pathogen) related factors. The immune response is controlled by a network of regulating pathways. LÄS MER