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Visar resultat 1 - 5 av 53 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Surgical Stress in Rats : The Impact of Buprenorphine on Postoperative Recovery

    Författare :Renée Sundbom; Klas Abelson; Kristina Dahlborn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgical stress; Corticosterone; Buprenorphine; Analgesia; Rats.; Försöksdjursvetenskap - Jämförande medicin; Comparative Medicine;

    Sammanfattning : During surgery, both anesthesia and tissue damage cause physiological stress responses in the body. The hypothalamic-pituitary-adrenal (HPA) axis is activated with increased levels of glucocorticoids. LÄS MER

  2. 2. Maternal separation in the rat : long-term effects of early life events on emotionality, drug response and neurobiology

    Författare :Maarit Marmendal; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Early deprivation; Alcohol intake; Anxiety; Corticosterone; Maternal separation; HPA axis; Maternal care; Monoamines;

    Sammanfattning : Exposure to early stress and emotional trauma in humans are associated with an increased risk to develop psychiatric disorders, for example, anxiety, depression and drug abuse. Furthermore, disruptions in stress hormone and neurotransmitter levels as well as structural changes in the brain have been connected to early adversities. LÄS MER

  3. 3. The effects of stress on atherosclerosis in mice

    Författare :Evelina Bernberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychosocial stress; Social isolation; Stressors; Social disruption stress; Atherosclerosis; Cytokines; Corticosterone; Metoprolol;

    Sammanfattning : Psychosocial stress has been recognized as an independent risk factor for cardiovascular disease and atherosclerosis. However, little is known about the mechanisms converting this psychosocial load into physical disease. LÄS MER

  4. 4. Taste Hedonics and the Intake of Alcohol and Food

    Författare :Anna Söderpalm; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Alcohol drinking; Adrenalectomy; Corticosterone; Cyanoketone; Food intake; Food restriction; GABA; Metyrapone; Taste reactivity; Benzodiazepine; Chlordiazepoxide; Cis Z -flupentixol; Diazepam; Flumazenil; Microinjections; Midazolam; Nucleus of the Solitary tract; Palatability; Parabrachial nucleus; Peduculopontine Tegmental Nucleus; Reward; 4th ventricle.;

    Sammanfattning : This thesis includes four papers based on animal experimental work. They analyze the way in which activation of a specific motivational state - hunger- modulates the rewarding actions of alcohol and taste palatability. LÄS MER

  5. 5. Examining Female Resilience to Early Environmental Influences : Short- and long-term consequences on behaviour, HPA axis activity and alcohol intake after prolonged maternal separation

    Författare :Stina Lundberg; Erika Roman; Ingrid Nylander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; Adulthood; Corticosterone; Early-life stress; Handling; Maternal deprivation; Multivariate concentric square field; MCSF; Sex differences; Social play behavior; Stress reactivity; Supplier differences; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Early-life experiences are an important factor influencing further development of the individual. Adverse experiences early in life, such as various kinds of abuse or neglect, are types of early-life stress that can adversely affect an individuals health, as well as contribute to the development of an array of disorders later in life. LÄS MER