Sökning: "Rats."

Visar resultat 1 - 5 av 1352 avhandlingar innehållade ordet Rats..

  1. 1. Surgical Stress in Rats : The Impact of Buprenorphine on Postoperative Recovery

    Författare :Renée Sundbom; Klas Abelson; Kristina Dahlborn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgical stress; Corticosterone; Buprenorphine; Analgesia; Rats.; Försöksdjursvetenskap - Jämförande medicin; Comparative Medicine;

    Sammanfattning : During surgery, both anesthesia and tissue damage cause physiological stress responses in the body. The hypothalamic-pituitary-adrenal (HPA) axis is activated with increased levels of glucocorticoids. LÄS MER

  3. 2. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats

    Författare :Magnus Löfgren; Torbjörn Bäckström; Inga-Maj Johansson; Per Södersten; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; Biological research on drug dependence; Biologisk beroendeforskning; Endocrinology; Endokrinologi; Obstetrics and gynaecology; Obstetrik och gynekologi; Pharmacological research; Farmakologisk forskning; Obstetrics and gynaecology; Obstetrik och gynekologi; Psychology; Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). LÄS MER

  4. 3. Neurobiological Consequences of Social Conditions and Alcohol Exposure in Adolescent rats

    Författare :Linnea Granholm; Ingrid Nylander; Anne-Lie Svensson; Erika Roman; Maria Ellgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; alcohol; amphetamine; dopamine; dorsal striatum; dynorphin; endogenous opi- oids; enkephalin; high-speed chronoamperometry; housing conditions; rats; nociceptin orphanin FQ; radi- oimmunoassay; self-administration; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Adolescence represents a time of extensive reorganisation and maturation of brain circuits involved in emotions, motivation and cognition and it is a period particular sensitive for external stimuli. External stimuli can be both socio-environmental factors and exposure to exogenous compounds such as drugs of abuse (e.g. alcohol). LÄS MER

  5. 4. Parathyroid hormone for bone repair and implant fixation - Experiment in rats

    Författare :Ralf Skripitz; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PMMA-cement; torque; tensile tesst; Bone conduction chamber; PTH; rats; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Intermittently administered PTH is known to increase bone mass in osteoporosis models. We studied its effects in bone repair and implant fixation, using histological and mechanical techniques in rats. LÄS MER

  7. 5. Post-Ischemic Housing Conditions Influence On Gene Transcription And Translation After Permanent Focal Brain Ischemia In Rats

    Författare :Li-Ru Zhao; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; brain-derived neurotrophic factor; mRNA; nerve growth factor-induced gene A; corticosteroid receptors; in situ hybridization; Neurologi; neurophysiology; Neurology; neuropsychology; brain ischemia; enriched environment; neuropsykologi; neurofysiologi;

    Sammanfattning : Enriched environment (EE) housing significantly ameliorates neurological deficits induced by cortical brain ischemia without changing infarction size, suggesting that EE-related functional benefits are associated with neuronal plasticity events in the remaining tissue. Brain-derived neurotrophic factor (BDNF), nerve growth factor-induced gene A (NGFI-A) and corticosteroid receptors (mineralocorticoid receptor, MR; glucocorticoid receptor, GR) have been demonstrated to be involved in brain plasticity. LÄS MER