Sökning: "catalytic promiscuity"
Visar resultat 11 - 12 av 12 avhandlingar innehållade orden catalytic promiscuity.
11. Catalysis and Site-Specific Modification of Glutathione Transferases Enabled by Rational Design
Sammanfattning : This thesis describes the rational design of a novel enzyme, a thiolester hydrolase, derived from human glutathione transferase (GST) A1-1 by the introduction of a single histidine residue. The first section of the thesis describes the design and the determination of the reaction mechanism. LÄS MER
12. Sequence- and structure guided engineering of proteins and enzymes for biotechnology and health applications
Sammanfattning : Proteins are highly diverse and sophisticated biomolecules that represent a cornerstone of biological structure and function and have been exploited in man-made applications for thousands of years. Those proteins that facilitate chemical reactions at physiologically relevant time-scales are referred to as enzymes. LÄS MER