Sökning: "bronchoalveolar lavage"

Visar resultat 16 - 20 av 103 avhandlingar innehållade orden bronchoalveolar lavage.

1. 16. Aspects of inflammation in chronic obstructive pulmonary disease : a clinical study

   Författare :Magnus J Löfdahl; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Chronic pbstructive pulmonary disease; bronchoscopy; bronchoalveolar lavage; inflammation; flow cytometry; bronchial biopsies;

   Sammanfattning : Development of chronic obstructive pulmonary disease (COPD) involves an amplified inflammatory response to tobacco smoke that results in a limitation of airflow. At present, the mechanisms underlying these inflammatory processes are not fully understood and insight into these mechanisms could be obtained through comparison of the processes in patients with COPD and appropriate controls. LÄS MER

3. 17. Airway responses to NO2 and allergen in asthmatics

   Författare :Charlotte Barck; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Air pollution; nitrogen dioxide; asthma; allergic inflammation; eosinophil cationic protein; neutrophilic cells; bronchoalevolar lavage; nasal lavage; induced sputum;

   Sammanfattning : Nitrogen dioxide (N02), a gas produced by combustion, is a common environmental air pollutant. Individuals with asthma are more sensitive to N02 exposure than healthy subjects, according to results from controlled human-exposure studies. N02 can enhance the asthmatic response to inhaled allergen. LÄS MER

4. 18. Inflammatory mechansims in pulmonary sarcoidosis

   Författare :Mary Berlin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adhesion molecules; alveolitis; bronchoalveolar lavage; bronchial hyperreactivity; extracellular matrix molecules; extrinsic allergic alveolitis; fibrosis; HLA-DR; sarcoidosis; TCR;

   Sammanfattning : Pulmonary sarcoidosis is an inflammatory disorder of unknown aetiology, characterised by an accumulation of CD4+ T-cells in the alveolar compartment and by granuloma formation and varying degrees of interstitial fibrosis. The initial clinical presentation may either be acute with fever, malaise, arthritis and/or erythema nodosum or insidious with cough, dyspnea, tiredness, and loss of weight. LÄS MER

5. 19. Large organic aerosols in a human exposure chamber : applications in occupational dermatology and lung medicine

   Författare :Lennart Lundgren; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Aerosol; bakery dust; bronchoalveolar lavage; chamber design; dermal exposure; exposure chamber; inhalation; large organic aerosols; mannequin; neutralizer; particle size; pinewood dust; skin;

   Sammanfattning : Exposure to large organic aerosol particles may cause respiratory and skin reactions. The use of human exposure chambers offers possibilities for experimental exposure challenges carried out with patients, in research and for investigations of the effects of exposure on the skin and in the respiratory tract. LÄS MER

7. 20. Interleukin-17 in models of neutrophilic lung disease

   Författare :Stefan Ivanov; Göteborgs universitet; []
   Nyckelord :Interleukin-17; Interleukin-23; Matrix metalloproteinase-9; neutrophils; macrophages; CD4 cells; innate response; lungs;

   Sammanfattning : Several acute or chronic lung disorders like adult respiratory distress syndrome, acute severe asthma, chronic obstructive pulmonary disease, chronic lung allograft rejection and cystic fibrosis, are associated with signs of an excess innate response in the bronchoalveolar space. Neutrophils may play a pathogenic role in these lung diseases by contributing to non-specific bronchial hyperresponsiveness and bronchial hypersecretion, as well as to epithelial damage and tissue remodelling. LÄS MER