Sökning: "bronchoalveolar lavage"

Visar resultat 11 - 15 av 103 avhandlingar innehållade orden bronchoalveolar lavage.

1. 11. Minimally invasive cardiorespiratory monitoring and lung recruitment manoeuvres. Studies in animals and humans

   Författare :Helena Odenstedt; Göteborgs universitet; []
   Nyckelord :Monitoring; cardiac output; lung volume; lung recruitment manoeuvre; regional ventilation; acute lung injury; bronchoalveolar lavage; endotoxin; cardiac tamponade;

   Sammanfattning : Background: The maintenance of adequate oxygen delivery is essential to preserve organ function. The circulatory and respiratory systems interact closely to accomplish this. Optimising the function of these systems is of fundamental importance in critically ill patients. This requires adequate monitoring techniques. LÄS MER

3. 12. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

   Författare :Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

   Sammanfattning : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. LÄS MER

4. 13. Multi-platform metabolomics assays to study the responsiveness of the human plasma and lung lavage metabolome

   Författare :Masoumeh Karimpour; Malin Nording L.; Magnus Åberg; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LC MS; GC MS; NMR; metabolomics; metabolite; exposure; postprandial; plasma; lung lavage; BW; BW; data analysis; univariate analysis; multivariate analysis;

   Sammanfattning : Metabolomics as a field has been used to track changes and perturbations in the human body by investigating metabolite profiles indicating the change of metabolite levels over time and in response to different challenges. In this thesis work, the main focus was on applying multiplatform-metabolomics to study the human metabolome following exposure to perturbations, such as diet (in the form of a challenge meal) and exhaust emissions (air pollution exposure in a controlled setting). LÄS MER

5. 14. Bronchoalveolar lavage and serum protein patterns in healthy individuals and sarcoidosis patients : a proteomics approach

   Författare :Fariba Sabounchi Schütt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Sarcoidosis; BALF; serum; proteomics; 2-D electrophoresis; protein-spot pattern; protein identification;

   Sammanfattning : The etiology of sarcoidosis remains unknown. Although biochemical changes are frequently observed in sarcoidosis, the problem of finding distinct biomarkers remains. Only a few markers are defined in this disease. LÄS MER

7. 15. Sarcoidosis : expression of cell regulatory markers and the influence of patient phenotype on bronchoalveolar lavage cell differential counts

   Författare :Muntasir Abo Al Hayja; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Sarcoidosis is a systemic inflammatory disease that can affect almost any organ, but the respiratory system is affected in more than 90% of the cases. To elicit an immune response, an antigen(s) is processed by antigen-presenting cells (APCs), e.g. LÄS MER