Sökning: "binding sites"

Visar resultat 26 - 30 av 696 avhandlingar innehållade orden binding sites.

  1. 26. Catalysis by theta-class glutathione transferases : Substrate binding, product formation and product release

    Författare :Per Jemth; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Glutathione transferases (GSTs) are detoxication enzymes that catalyze theconjugation of glutathione to a large number of electrophilic molecules. In this waythey help to rid cells of potentially toxic substances. This thesis deals with thecatalysis afforded by Theta-class glutathione transferases. LÄS MER

  3. 27. Profilin:actin in cell motility : A search for profilin:actin binding proteins

    Författare :Thomas Johansson; Roger Karlsson; Björn Öbrink; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; profilin; actin; Cell biology; Cellbiologi;

    Sammanfattning : The profilin:actin complex is a major source of actin for actin filament growth in vivo. A number of proteins regulating either profilin or actin has been described since profilin:actin was isolated during the 1970s. Since then, profilin and actin and their binding partners have been intensively studied. LÄS MER

  4. 28. Ribosome standby sites and other structural aspects of translation initiation regions in Escherichia coli

    Författare :Maaike M. Sterk; Gerhart E. H. Wagner; Fredrik Söderbom; Isabella Moll; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome standby sites; translation initiation; mRNA structure; bacteria;

    Sammanfattning : Translation initiation, which is rate-limiting in protein synthesis, is often the step at which regulation occurs. Here, we investigated several mechanisms of translation initiation in Escherichia coli, including their control. LÄS MER

  5. 29. Multiple amyloid binding sites in Alzheimer brain and their interaction with synaptic and inflammatory mechanisms

    Författare :Ruiqing Ni; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer’s disease (AD) is the most common type of dementia. A series of pathophyslogical changes start many years prior to the emergence of clinical symptoms. LÄS MER

  7. 30. From Structure to Function with Binding Free Energy Calculations for Codon Reading, Riboswitches and Lectins

    Författare :Johan Sund; Åqvist Johan; Javier Luque; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; binding free energy; ribosome; codon reading; release factor; mitochondrial translation; purine riboswitch; lectin; molecular dynamics; free energy perturbation; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : Molecular association is part of many important processes in living cells. Computational methods for calculating binding free energies allows for a quantitative examination of biomolecular structures and hypotheses drawn from biochemical experiments. LÄS MER