Sökning: "bacterial toxins"

Visar resultat 16 - 20 av 62 avhandlingar innehållade orden bacterial toxins.

  1. 16. Glucosyltransferase toxins from clostridia : molecular interactions with cells

    Författare :Esteban Chaves Olarte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : An enzymatic activity was recently described for the group of Large Clostridial Cytotoxins (LCTs). This activity is glucosyltransfer and consists in the covalent addition of glucose, from UDP-glucose (UDP-Glc) to threonine 35 of small GTPases of the Rho subfamily. LÄS MER

  3. 17. Effects of bacterial toxins, surgical trauma and aging on middle and inner ear structure and function : an experimental study in the rat

    Författare :Monika Stenqvist; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 18. Bacterial genotoxins : an interface between infection and cancer biology

    Författare :Laura Levi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Infections contribute to the development of more than 20% of all malignancies in humans. While strong evidence exists for a number of virus-associated cancers, the role of bacterial infections is still poorly appreciated although there are evidences that link chronic bacterial infections to increased risk of certain tumors. LÄS MER

  5. 19. Studies on O-glycosylation of mucin-type proteins and their binding to antibodies, bacterial toxins and viral receptors

    Författare :Stefan Gaunitz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Carbohydrates are ubiquitous on the surface of all cells in mammals where they are involved in interactions with the surroundings (extracellular matrix), other cells (including self and non-self) and microbes (bacteria and virus). Carbohydrate-protein interactions in nature are often mediated via multivalent binding where the combined strength of multiple receptor- ligand interactions results in a binding that is highly specific and strong. LÄS MER

  7. 20. Structural analyses of carbohydrate receptors for enterotoxins and adhesins of enterotoxigenic Escherichia coli

    Författare :Dani Zalem; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carbohydrate recognition; glycosphingolipid; diarrheagenic E. coli; ETEC; heat-labile enterotoxin; colonization factor; AB5 toxins;

    Sammanfattning : Carbohydrate-binding proteins expressed by microbes are key determinants in initiating and sustaining infections that account for millions of deaths each year. This thesis fo- cused on proteins integral to infections instigated by enterotoxigenic Escherichia coli (ETEC); estimated as the largest bacterial cause of diarrhea in the world with hundreds of millions of cases each year. LÄS MER