Sökning: "aquaporin 3"

Visar resultat 11 - 15 av 20 avhandlingar innehållade orden aquaporin 3.

  1. 11. The importance of Foxi1 expression in kidney and inner ear

    Författare :Sandra Rodrigo Blomqvist; Göteborgs universitet; []
    Nyckelord :Foxi1; intercalated cells; endolymphatic sac; acid base regulation;

    Sammanfattning : The forkhead (FOX) genes comprise a family of transcription factors involved in generegulation in both embryonic and adult tissue. Foxi1 is expressed in the kidney andthe developing inner ear. We examined the significance of Foxi1 in these two organsand explain the molecular mechanisms behind the phenotype seen in Foxi1 deficientmice. LÄS MER

  3. 12. Studies on the oxysterol receptor LXRβ : linking cholesterol metabolism to water transport and cell proliferation

    Författare :Chiara Gabbi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Liver X Receptor β (LXRβ) is a nuclear receptor, belonging to the superfamily of ligand-­activated transcription factors. With its α isoform (LXRα), LXRβ shares more than 78% homology in its amino acid sequence, a common profile of oxysterol ligands and the heterodimerization partner, Retinoid X Receptor. LÄS MER

  4. 13. Plant Membrane Proteomics - using isolated membranes and proteins to compare and quantify subproteomes

    Författare :Katja Bernfur; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; quantification; proteomics; metabolic labeling; plasma membrane;

    Sammanfattning : Membrane proteins are particularly important to characterize, since they are involved in cellular processes of utmost importance in control and regulation of cells, such as transport across membranes, signal transduction and photosynthesis. The word "proteome" means all proteins expressed by a e.g. LÄS MER

  5. 14. Studies on astrocyte function : potential roles in brain water homeostasis and neuroprotection

    Författare :Yutong Song; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Astrocytes are essential in brain homeostasis and function, including maintenance of water and ion balance. Astrocytes express the water channel aquaporin 4 (AQP4), implicated in both physiological functions and injury processes associated with brain edema, a common consequence of brain diseases. LÄS MER

  7. 15. Studies on the phenotype of LXRβ-/- mice : from malabsorption to amyotrophic lateral sclerosis

    Författare :Chiara Gabbi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Liver X Receptors, LXRalpha and LXRbeta (NR1H2) are nuclear receptors belonging to the superfamily of ligand-activated transcription factors with a key role in the control of lipid and glucose metabolism. Studies of the phenotype of LXRalpha-/-mice and LXRbeta-/-mice have shown that these nuclear receptors have specific and distinct roles, although they share very high sequence homology (78%). LÄS MER