Sökning: "Chiara Gabbi"

Hittade 2 avhandlingar innehållade orden Chiara Gabbi.

1. 1. Studies on the oxysterol receptor LXRβ : linking cholesterol metabolism to water transport and cell proliferation

   Författare :Chiara Gabbi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Liver X Receptor β (LXRβ) is a nuclear receptor, belonging to the superfamily of ligand-­activated transcription factors. With its α isoform (LXRα), LXRβ shares more than 78% homology in its amino acid sequence, a common profile of oxysterol ligands and the heterodimerization partner, Retinoid X Receptor. LÄS MER

3. 2. Studies on the phenotype of LXRβ-/- mice : from malabsorption to amyotrophic lateral sclerosis

   Författare :Chiara Gabbi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Liver X Receptors, LXRalpha and LXRbeta (NR1H2) are nuclear receptors belonging to the superfamily of ligand-activated transcription factors with a key role in the control of lipid and glucose metabolism. Studies of the phenotype of LXRalpha-/-mice and LXRbeta-/-mice have shown that these nuclear receptors have specific and distinct roles, although they share very high sequence homology (78%). LÄS MER