Sökning: "and failure"

Visar resultat 1 - 5 av 2787 avhandlingar innehållade orden and failure.

  1. 1. Heart failure : biomarker effect and influence on quality of life

    Författare :Patric Karlström; Urban Alehagen; Mikael Dellborg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart failure; Biomarker; B-type natriuretic peptide; Heart failure treatment; B-type Natriuretic Peptide guided heart failure treatment; Responders; Health-related quality of life; Heart failure duration; Outcomes;

    Sammanfattning : Background and aims: Heart failure (HF) is a life threatening condition and optimal handling is necessary to reduce risk of therapy failure. The aims of this thesis were: (Paper I) to examine whether BNP (B-type natriuretic peptide)-guided HF treatment improves morbidity and mortality when compared with HF therapy implemented by a treating physician at sites experienced in managing patients with HF according to guidelines; (Paper II) to investigate how to define a responder regarding optimal cut-off level of BNP to predict death, need for hospitalisation, and worsening HF and to determine the optimal time to apply the chosen cut-off value; (Paper III) to evaluate how Health-Related Quality of Life (HR-QoL) is influenced by natriuretic peptide guiding and to study how HR-QoL is affected in responders compared to non-responders; (Paper IV) to evaluate the impact of patient age on clinical outcomes, and to evaluate the impact of duration of the HF disease on outcomes and the impact of age and HF duration on BNP concentration. LÄS MER

  3. 2. Handling severe uncertainty in strategic project appraisal : Methods and applications of context analysis

    Författare :Anton Talantsev; Aron Larsson; David Sundgren; John Ward; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Decision Intelligence; Deep Uncertainty; Scenario Analysis; Multiple Criteria Decision Analysis; Simulation; Context Analysis; Project Appraisal; Risk Assessment; Threat and Opportunity; Computer and Systems Sciences; data- och systemvetenskap;

    Sammanfattning : The long-term success or failure of a strategic project is largely shaped by its context. Therefore, the assessment of the external factors influencing the fulfilment of project long-term goals is vital for the effective project appraisal and planning. LÄS MER

  4. 3. How to create and analyze a Heart Failure Registry with emphasis on Anemia and Quality of Life

    Författare :Åsa Jonsson; Ulf Dahlström; Magnus Edner; Lars Lund; Bertil lindahl; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart failure; reduced ejection fraction; mid-­‐range ejection fraction; preserved ejection fraction; anemia; Health-­‐related quality of life; observational study; outcomes;

    Sammanfattning : Background and aimsHeart failure (HF) is a major cause of serious morbidity and death in the population and one of the leading medical causes of hospitalization among people older than 60 years. The aim of this thesis was to describe how to create and how to analyze a Heart Failure Registry with emphasis on Anemia and Quality of Life. LÄS MER

  5. 4. Glory and failure : The difference engines of Johann Müller, Charles Babbage and Georg and Edvard Scheutz

    Författare :Michael Lindgren; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN;

    Sammanfattning : This book presents a social and technical analysis of the first attempts to mechanize the production of numerical tablets. It deals with an age when the word "computer" denoted a human being and not a machine. LÄS MER

  7. 5. Shear Fracture and Delamination in Packaging Materials : A study of Experimental Methods and Simulation Techniques

    Författare :Md. Shafiqul Islam; Sharon Kao-Walter; Christian Johansson; Johan Tryding; Blekinge Institute of Technology; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Package opening; Shear test specimen; Stress intensity factor; Finite Element simulation; Scanning electron microscopy; Polymers; Interlaminar shear delamination;

    Sammanfattning : Packages are the means of preservation, distribution and convenience of use for food, medicine and other consumer products. Package opening is becoming complicated in many cases because of cutting cost in design and production of opening techniques. LÄS MER