Sökning: "Mikael Dellborg"

Hittade 3 avhandlingar innehållade orden Mikael Dellborg.

1. 1. Heart failure : biomarker effect and influence on quality of life

   Författare :Patric Karlström; Urban Alehagen; Mikael Dellborg; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart failure; Biomarker; B-type natriuretic peptide; Heart failure treatment; B-type Natriuretic Peptide guided heart failure treatment; Responders; Health-related quality of life; Heart failure duration; Outcomes;

   Sammanfattning : Background and aims: Heart failure (HF) is a life threatening condition and optimal handling is necessary to reduce risk of therapy failure. The aims of this thesis were: (Paper I) to examine whether BNP (B-type natriuretic peptide)-guided HF treatment improves morbidity and mortality when compared with HF therapy implemented by a treating physician at sites experienced in managing patients with HF according to guidelines; (Paper II) to investigate how to define a responder regarding optimal cut-off level of BNP to predict death, need for hospitalisation, and worsening HF and to determine the optimal time to apply the chosen cut-off value; (Paper III) to evaluate how Health-Related Quality of Life (HR-QoL) is influenced by natriuretic peptide guiding and to study how HR-QoL is affected in responders compared to non-responders; (Paper IV) to evaluate the impact of patient age on clinical outcomes, and to evaluate the impact of duration of the HF disease on outcomes and the impact of age and HF duration on BNP concentration. LÄS MER

3. 2. Risk factors for incident heart failure and atrial fibrillation in an elderly population : The role of cardiac conduction and heart rate variability

   Författare :Bozena Ostrowska; Carina Blomström Lundqvist; Lars Lind; Mikael Dellborg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; incident heart failure; incident atrial fibrillation; prediction of heart failure; short P-wave duration; heart rate variability.; Cardiology; Kardiologi;

   Sammanfattning : Heart failure (HF) and atrial fibrillation (AF) are epidemic diseases, frequently coexisting, sharing risk factors and conferring poor prognosis. Identification of individuals at high risk of HF and AF may enable early treatment and improve the prognosis. Reliable prediction models for daily clinical practice are lacking. LÄS MER

4. 3. Diagnostic and Prognostic Evaluation in Postmenopausal Women with Signs and Symptoms of Unstable Coronary Artery Disease

   Författare :Kåge Säfström; Mikael Dellborg; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Coronary artery disease (CAD) is the major cause of death in both men and women in the western world. The majority of studies undertaken to evaluate diagnostic methods, risk stratification and treatment of CAD, have been performed on men. LÄS MER