Sökning: "adherens junctions"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden adherens junctions.

  1. 1. Regulation of E-cadherin mediated adhesion in thyroid epithelial cells

    Författare :Fredrik Larsson; Göteborgs universitet; []
    Nyckelord :thyroid; adherens junction; E-cadherin; thyrotropin; cAMP; PKA; Epac; IQGAP;

    Sammanfattning : Cell adhesion is one of multicellular organisms most fundamental features. Cells connect to each other by transmembrane proteins arranged in junction complexes. LÄS MER

  3. 2. Differential expression pattern of CEACAM1 isoforms in polarized epithelial cells : it's regulation and some functional consequences

    Författare :Ulla Sundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CEACAM1; adhesion; lateral localization; adherens junctions; desmosomes; primary cilia;

    Sammanfattning : The cell adhesion molecule CEACAM1 is expressed in epithelia, small vessel endothelia and leukocytes as two major, co-expressed isoforms, CEACAM1-L and CEACAM1-S, which differ in their cytoplasmic domains. CEACAM1 has been found both in cell-cell contact areas and on apical surfaces of polarized epithelial cells. LÄS MER

  4. 3. The role of angiomotin in endothelial cell motility and cell-cell junction formation

    Författare :Anders Bratt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiogenesis; cancer; angiostatin; angiomotin; cell motility cell-cell junction; tight junction; adherens junction;

    Sammanfattning : Clinical as well as pre-clinical data show that tumor growth can be restrained by inhibiting angiogenesis. We have been investigating the mechanism of action of angiostatin, an inhibitor of angiogenesis, in order to design novel therapies against cancer. LÄS MER

  5. 4. Wnt signaling affects cell adhesion and neuronal differentiation

    Författare :Maria Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The tube itself becomes the adult ventricular system. LÄS MER

  7. 5. Cytoskeleton-interacting proteins in brainstem development : roles of KCC2 and Vangl2

    Författare :Zachi Horn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The brainstem is the most evolutionary conserved division of the brain. It develops from the hindbrain and midbrain regions of the neural tube and forms neural networks that regulate vital functions of the body. One of the most critical roles is to generate respiratory rhythm for the regulation of oxygen, carbon dioxide and pH levels. LÄS MER