Sökning: "adherens junction"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden adherens junction.
1. Regulation of E-cadherin mediated adhesion in thyroid epithelial cells
Sammanfattning : Cell adhesion is one of multicellular organisms most fundamental features. Cells connect to each other by transmembrane proteins arranged in junction complexes. LÄS MER
2. Tight juntion in ovarian surface epithelium and epithelial ovarian tumors
Sammanfattning : Epithelial ovarian cancer originating from ovarian surface epithelium (OSE) is the most lethal type of gynecological cancer among women worldwide. The poor understanding of the cellular and molecular events associated with ovarian carcinogenesis leads to difficulties in early diagnosis and in efficient treatment. LÄS MER
3. The role of angiomotin in endothelial cell motility and cell-cell junction formation
Sammanfattning : Clinical as well as pre-clinical data show that tumor growth can be restrained by inhibiting angiogenesis. We have been investigating the mechanism of action of angiostatin, an inhibitor of angiogenesis, in order to design novel therapies against cancer. LÄS MER
4. Differential expression pattern of CEACAM1 isoforms in polarized epithelial cells : it's regulation and some functional consequences
Sammanfattning : The cell adhesion molecule CEACAM1 is expressed in epithelia, small vessel endothelia and leukocytes as two major, co-expressed isoforms, CEACAM1-L and CEACAM1-S, which differ in their cytoplasmic domains. CEACAM1 has been found both in cell-cell contact areas and on apical surfaces of polarized epithelial cells. LÄS MER
5. The Role of Paladin in Endothelial Cell Signaling and Angiogenesis
Sammanfattning : Angiogenesis, the formation of new blood vessels from a pre-existing vasculature, is crucial during development and for many diseases including cancer. Despite tremendous progress in the understanding of the angiogenic process, many aspects are still not fully elucidated. LÄS MER