Sökning: "The relationship between reduced renal function and cardiovascular disease"

Hittade 3 avhandlingar innehållade orden The relationship between reduced renal function and cardiovascular disease.

  1. 1. The relationship between reduced renal function and cardiovascular disease

    Författare :Patrik Svensson; Kardiovaskulär forskning - hypertoni; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; eGFR; creatinine; cystatin C; CKD-EPI; CKD; CVD; Genetics; Blood Pressure; Hypertension;

    Sammanfattning : This thesis examines the relationship between measures of renal function and cardiovascular disease (CVD) in patients with hypertension (the NORDIL study) and in the healthy population (Malmö Diet and Cancer Study, MDC) and whether antihypertensive treatment response and the risk of CVD is affected by genetic variation of a regulator of the renal amiloroide sensitive sodium channel (NORDIL). In study 1 we tested creatinine, estimated glomerular filtration rate (eGFR) with Cockroft-Gault (CG) and the MDRD equations and also microalbuminuria (MA) as predictors of CVD, stroke and CVD death. LÄS MER

  3. 2. Endothelium-Dependent Vasodilation and Oxidative Stress in Chronic Renal Failure

    Författare :Margus Annuk; Ola Samuelson; Uppsala universitet; []
    Nyckelord :Medical sciences; endothelium; oxidative stress; chronic renal failure; L-arginine; diclofenac; erythropoietin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Internal Medicine; invärtesmedicin;

    Sammanfattning : Cardiovascular disease (CVD) is the major cause of death in patients with chronic renal failure (CRF). Endothelial function and oxidative stress (OS) have previously been shown to be important in the pathogenesis of CVD. In this thesis, the endothelium-dependent vasodilatation (EDV) and OS were investigated in the patients with CRF. LÄS MER

  4. 3. Fat mass, adipokines and clinical complications of chronic kidney disease

    Författare :Jonas Axelsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chronic kidney disease; end-stage renal disease; insulin resistance; inflammation; cardiovascular disease; adipokines; leptin; epoetin; resistin; visfatin; AHSG; CD163; outcome.;

    Sammanfattning : Patients with chronic kidney disease (CKD), irrespective of initial etiology, have a risk of cardiovascular morbidity (CVD) and mortality that is many-fold higher than that of a similar person without CKD. While traditional risk factors, such as hyperlipidemia, certainly contribute, these factors cannot by themselves explain the burden of CVD. LÄS MER