Sökning: "Th1 Th2 balance"

Visar resultat 21 - 25 av 25 avhandlingar innehållade orden Th1 Th2 balance.

  1. 21. Immunomodulation by intravenous immunoglobulin : the effect on cytokine production studied at the single-cell level

    Författare :Ulrika Skansén-Saphir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Preparations of pooled human immunoglobulin for intravenous use (IVIg) have an established therapeutic role in immunodeficiencies, Idiopathic Thrombocytopenic Purpura and Kawasaki's disease and has been attempted in other immunologically mediated conditions including autoimmunity, malignancies, bone marrow transplantation and serious infections such as group A streptococcal toxic shock syndrome. The effects of IVIg on cytokine synthesis in peripheral blood mononuclear cells (PBMC) was studied in vitro by applying a new immunohistochemical method for detection of cytokine production at a single cell level. LÄS MER

  3. 22. Immune regulation in multiple sclerosis : cytokines and metalloproteinases

    Författare :Volkan Özenci; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immunological mechanisms play a central role in the pathogenesis sclerosis (MS). In this study two groups of related immune variables are cytokines and metalloproteinases (MMPs), which regulate each other's production and activation. LÄS MER

  4. 23. Clinical, epidemiological and immunological aspects of Lyme borreliosis with special focus on the role of the complement system

    Författare :Anna J Henningsson; Jan Ernerudh; Pia Forsberg; Kristina Nilsson Ekdahl; Bo-Eric Malmvall; Lars Hagberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lyme borreliosis; neuroborreliosis; clinical; epidemiology; inflammation; complement; cytokine; chemokine;

    Sammanfattning : Lyme borreliosis (LB) is the most common vector-borne disease in the Northern Hemisphere. The infection is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato complex, and it is transmitted to humans by ticks. LÄS MER

  5. 24. Cellular and molecular mechanisms in immune mediated hepatic fibrosis. A study of the inflammatory syndrome and fibrosis development of the NIF mouse liver

    Författare :Julia Nilsson; Autoimmunitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibrosis; liver; mouse model; NKT cells; type 2 inflammation; inflammasome;

    Sammanfattning : Fibrosis is the result of dysregulated inflammation and tissue repair, and is characterized by the excessive accumulation of extra cellular matrix (ECM) proteins. It causes detrimental effects to the afflicted tissue and can subsequently lead to organ failure. LÄS MER

  7. 25. Immunopathogenesis of Guillain-Barré syndrome and chronic inflammatory demyelinating polyradoculoneuropathy

    Författare :Rayomand Press; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Guillain-Barre syndrome (GBS) is an inflammatory polyradiculoneuropathy with acute onset and usually a spontaneous recovery. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic progressive inflammatory neuropathy. GBS and CIDP are associated with high morbidity despite treatment with immunomodulatory drugs. LÄS MER