Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Overlapping Neural Substrates of Alcohol- and Anxiety-Related Behavior in the Rat

   Författare :Riccardo Barchiesi; Estelle Barbier; Markus Heilig; Annika Thorsell; Andrew Holmes; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alcohol use disorder; Anxiety disorder; Behavior; Rat; Prelimbic cortex; Amygdala; Basolateral amygdala; Stress; Epigenetics; Syt1; Prdm2; Avp; Conditioned fear; Social defeat stress; Witness stress; Susceptibility; Resilience;

   Sammanfattning : Alcohol use is a leading cause of death and disease worldwide. A large part of this disease burden is associated with alcohol use disorder (AUD), a diagnostic category characterized by excessive use in spite of negative consequences ("compulsive use"), a loss of control over intake, and choice of alcohol over natural rewards. LÄS MER

3. 2. Membrane lipids and their transfer proteins in β-cells

   Författare :Beichen Xie; Olof Idevall-Hagren; Anders Tengholm; Jen Liou; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ca2 ; PKC; E-Syt1; TMEM24; ER-PM contact; PI 4; 5 P2; phosphoinositides; β-cell; insulin; optogenetics; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

   Sammanfattning : Insulin secretion from β-cells is essential for glucose homeostasis and is often dysregulated in diabetes. Intracellular Ca2+ and membrane lipids cooperate to control insulin secretion with high spatial and temporal precision. LÄS MER