Sökning: "Markus Heilig"

Hittade 3 avhandlingar innehållade orden Markus Heilig.

  1. 1. Overlapping Neural Substrates of Alcohol- and Anxiety-Related Behavior in the Rat

    Författare :Riccardo Barchiesi; Estelle Barbier; Markus Heilig; Annika Thorsell; Andrew Holmes; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alcohol use disorder; Anxiety disorder; Behavior; Rat; Prelimbic cortex; Amygdala; Basolateral amygdala; Stress; Epigenetics; Syt1; Prdm2; Avp; Conditioned fear; Social defeat stress; Witness stress; Susceptibility; Resilience;

    Sammanfattning : Alcohol use is a leading cause of death and disease worldwide. A large part of this disease burden is associated with alcohol use disorder (AUD), a diagnostic category characterized by excessive use in spite of negative consequences ("compulsive use"), a loss of control over intake, and choice of alcohol over natural rewards. LÄS MER

  3. 2. From social drinking to alcohol addiction : Decision making and its neural substrates along a spectrum from social drinking to alcohol addiction

    Författare :Hanna Karlsson; Irene Perini; Markus Heilig; Bo Söderpalm; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alcohol; heavy drinking; alcohol addiction; decision making; alcohol choice; fMRI; rTMS;

    Sammanfattning : For a minority of alcohol users, the initial sip of alcohol marks the start of a life-threatening process. This thesis studies cognitive mechanisms pertinent to alcohol addiction and its development, using a spectrum of individuals that range from healthy social drinkers, through people with hazardous use, to those suffering from alcohol addiction. LÄS MER

  4. 3. Studies on Variability in Olanzapine Disposition

    Författare :Elisabeth Skogh; Staffan Hägg; Marja Liisa Dahl; Markus Heilig; Lena Flyckt; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Schizophrenia and schizoaffective disorders are chronic conditions with a significant impact on many functions. Positive, negative, cognitive and motor symptoms appear in different degrees and constellations. Antipsychotics are of fundamental importance to reduce symptoms. LÄS MER