Sökning: "SIV model"

Visar resultat 11 - 15 av 31 avhandlingar innehållade orden SIV model.

  1. 11. Pain, fatigue and fear-avoidance beliefs in relation to physical activity and body awareness in persons diagnosed with rheumatoid arthritis

    Författare :Helena Lööf; Unn-Britt Johansson; Elisabet Welin Henriksson; Staffan Lindblad; Siv Söderberg; Sophiahemmet Högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; Body awareness; Pain; Fatigue; Fear-avoidance beliefs about physical activity; Physical activity; Coping strategies; Cross-cultural adaptation; Concurrent think-aloud interviews; Narrative interviews; Phenomenological; Cross-sectional; Psychometrics; Rheumatoid Arthritis;

    Sammanfattning : Introduction: Pain and fatigue are highly common and a major concern for persons diagnosed with rheumatoid arthritis (RA). Having physical limitations, which have a significant effect on daily life, is also described as a major problem for persons with RA. LÄS MER

  3. 12. Genome Evolution of Neurospora tetrasperma

    Författare :Yu Sun; Hanna Johannesson; Siv Andersson; Toni Gabaldon; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neurospora tetrasperma; next-generation sequencing; introgression; intron; chromosomal inversion; codon usage; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : In this thesis work, I have used a comparative genomics approach to study a fungal model organism, Neurospora tetrasperma. My specific focus has been on genomic introgression, intron evolution, chromosomal structural rearrangements and codon usage. LÄS MER

  4. 13. Causes of Substitution Frequency Variation in Pathogenic Bacteria

    Författare :Wagied Davids; Siv Andersson; Otto Berg; Bengt Persson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Comparative genomics; Molecular evolution; Bioinformatics; Human pathogens; Rickettsia; Helicobacter pylori; Biologi; Biology; Biologi;

    Sammanfattning : Estimating substitution frequencies at sites that influence (Ka) and do not influence (Ks) the amino acid sequence is important for understanding the dynamics of molecular sequence evolution and the selective pressures that have shaped genetic variation. The aim of this work was to gain a deeper understanding of the driving forces of substitution frequency variation in human pathogens. LÄS MER

  5. 14. Lifestyle and Genome Evolution in Vector-Borne Bacteria : A Comparison of Three Bartonella Species

    Författare :Anna Carolin Frank; Siv Andersson; Stewart Cole; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Bartonella; evolution; host-restriction; vector-borne; horizontal gene transfer; genome reduction; alpha-proteobacteria; Type-IV secretion; Biologi; Biology; Biologi;

    Sammanfattning : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. LÄS MER

  7. 15. Evolutionary Processes and Genome Dynamics in Host-Adapted Bacteria

    Författare :Björn Nystedt; Siv Andersson; David Guttman; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molecular evolution; pathogen; secretion system; Bartonella; Buchnera; Blochmannia; Helicobacter; Bioinformatics; Bioinformatik; Evolutionary Genetics; evolutionär genetik;

    Sammanfattning : Many bacteria live in close association with other organisms such as plants and animals, with important implications for both health and disease. This thesis investigates bacteria that are well adapted to live inside an animal host, and describes the molecular evolutionary processes underlying host-adaptation, based on bacterial genome comparisons. LÄS MER