Avancerad sökning

Hittade 4 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. LKB1 signaling pathways in adipocytes - Focus on the AMPK-related kinase SIK2

    Författare :Emma Henriksson; Proteinfosforylering; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; signal transduction; protein phosphorylation; LKB1; SIK2; SIK3; cAMP;

    Sammanfattning : Adipose tissue does not only store and release energy in response to hormones, it is also known as an endocrine organ, secreting important factors and hormones that influence for example appetite and insulin sensitivity. The association of type 2 diabetes with obesity has been known for quite some time. LÄS MER

  3. 2. Salt-inducible kinases in adipose tissue

    Författare :Johanna Sernevi Säll; Proteinfosforylering; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; salt-inducible kinase; SIK; SIK2; fettväv; fettceller; insulinsignalering; glukosupptag; fetma; insulinresistens; salt-inducible kinase; SIK; SIK2; adipose tissue; adipocytes; insulin signalling; glucose uptake; obesity; insulin resistance;

    Sammanfattning : Obesity, insulin resistance and type 2 diabetes (T2D) are metabolic diseases that increase rapidly in the modern society. The underlying mechanisms are complex and involve both environmental and genetic factors. Adipose tissue is an important organ for maintaining whole body energy homeostasis. LÄS MER

  4. 3. Relevance of the salt-inducible kinase network for the development of high blood pressure and cardiac hypertrophy

    Författare :Sergej Popov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hypertension (high blood pressure) is a multifactorial condition that remains a big worldwide problem. 95% of all hypertensive people suffer from essential hypertension with unknown causes. This can cause different heart diseases such as cardiac hypertrophy (CH), a condition which can ultimately lead to heart failure. LÄS MER

  5. 4. Novel aspects of metabolic regulation and inflammation in human adipocytes

    Författare :Annie Pettersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The significance of adipose tissue and obesity has been recognized in numerous pathologies. However, the mechanisms behind this connection are not yet completely understood. LÄS MER