Sökning: "Regulatory T cells"

Visar resultat 16 - 20 av 423 avhandlingar innehållade orden Regulatory T cells.

  1. 16. Regulatory properties of dendritic cells and B cells in adaptive immunity

    Författare :Bengt Johansson Lindbom; Adaptivt immunförsvar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; Cellular differentiation; Cytokines; Dendritic cells; B lymphocytes; T lymphocytes;

    Sammanfattning : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. LÄS MER

  3. 17. On the induction and function of Foxp3+ regulatory T cells

    Författare :Cecilia Oderup; Diabetes - immunovirologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; transplantation; regulatory T cell; serology; Immunology; superantigen; costimulation; dendritic cell; Foxp3;

    Sammanfattning : This thesis is based on three original papers with the overall aim to study the mechanisms of induction and function of Foxp3+CD4+CD25+ regulatory T cells. Regulatory T cells induce down-modulation of costimulatory molecules CD80 and CD86 on dendritic cells in vitro. LÄS MER

  4. 18. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa

    Författare :Silvia Melgar; Nadine Cerf-Bensussan; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intestinal mucosa; intraepithelial lymphocyte; lamina propria lymphocyte; γδ T cell; regulatory T cell; cytotoxicity; cytokine; basal lymphoid aggregate; ulcerative colitis; Crohn s disease;

    Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER

  5. 19. T cell signatures and modulation by regulatory T cells

    Författare :Rubin Narayan Joshi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : CD4 T cells are crucial coordinators of protective immune responses against microbes and tumors. However, immune responses misdirected towards self-antigens are the hallmarks of autoimmune diseases. Regulatory T cells (Tregs) maintain peripheral immune tolerance, mainly by suppressing effector T cells. LÄS MER

  7. 20. CD25+CD4+ regulatory T cells in rheumatic disease

    Författare :Duojia Cao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human; rheumatic disease; synovial fluid; regulatory T cells; FOXP3; suppression; tolerance; autoimmunity;

    Sammanfattning : CD25+CD4+ T cells represent a unique cell lineage of thymus derived naturally occurring regulatory T cells. The gene Foxp3 (mouse)/ FOXP3(human) is strictly related to their generation in the thymus and their regulatory function in the periphery. LÄS MER