Sökning: "Premature menopause"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Premature menopause.

  1. 1. Epidemiological and Clinical Aspects of Hormonal Contraception and Menopausal Hormone Therapy in Women

    Författare :Micaela Sundell; Jan Brynhildsen; Anna-Clara Spetz Holm; Mats Fredrikson; Mikael Hoffmann; Ian Milsom; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hormonal contraceptives; Obesity; Menopausal hormone therapy; Hormone replacement therapy; Pulmonary embolism; Premature menopause; Pharmacoepidemiology;

    Sammanfattning : Background: The main indications for therapy with female sex hormones are contraception and menopausal hormone therapy (MHT). The aim of this thesis was to investigate the use of hormonal contraception and MHT in different populations of women in Sweden, 2000–2021. The use of contraception in women with obesity was studied. LÄS MER

  3. 2. The human ovary : a characterization of cell types and adverse ovarian side effects of chemotherapy

    Författare :Magdalena Wagner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human ovary has a major role in the body’s endocrine and reproductive system. Understanding its cell type composition is crucial in order to study underlying mechanisms of hormonal balance and ovarian follicle maturation in health and disease. The outer lining of the ovary, the cortex, harbors the ovarian reserve. LÄS MER

  4. 3. Molecular studies of intra-oocyte phosphatidylinositol 3 kinase (PI3K) signaling pathway in controlling female fertility

    Författare :Pradeep Reddy Dubbaka Venu; Kui Liu; Evelyn Telfer; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primordial follicles; Oocyte; PI3K; Biochemistry; Biokemi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : The primordial follicle pool is the main source of developing follicles in the ovary. The length of reproductive life and the onset of menopause are governed by the amount of primordial follicles in the ovary. LÄS MER

  5. 4. Studies of side effects related to adjuvant breast cancer regimens with focus on chemotherapy

    Författare :Andri Papakonstantinou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Radiotherapy, endocrine therapy, chemotherapy and targeted therapy adjunct to surgery have a critical role in the management of early breast cancer for outcome improvement. Anthracycline containing chemotherapy reduces 10-year incidence of breast cancer mortality by an absolute 6. LÄS MER

  7. 5. Molecular pathways mediating the development of female germ cells

    Författare :Sanjiv Risal; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Ovary; primordial follicles; primordial germ cells; Oogonial stem cells;

    Sammanfattning : In mice, primordial germ cells (PGCs) dramatically increase in their number from 200 cells at 9.5 dpc to 10 000 cells at 12.5 dpc with doubling time of 12.6 hours. LÄS MER