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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Microbial ecology in deep granitic groundwater - activity and impact of viruses

    Författare :Hallgerd Eydal; Göteborgs universitet; []
    Nyckelord :ATP; Desulfovibrio; groundwater; bacteriophage; Podoviridae; sulphate-reducing bacteria; viral ecology;

    Sammanfattning : The deep subsurface environments in granitic rock can be studied and sampled at the Äspö hard rock laboratory (HRL) close to Oskarshamn in Sweden. Here, the groundwater is anaerobic and total counts give numbers of 104 to 106 cells mL-1. However, these measurements do not reveal if the cells are active and alive. LÄS MER

  2. 2. Bacterial viruses targeting multi-resistant Klebsiella pneumoniae and Escherichia coli

    Författare :Harald Eriksson; Anders Nilsson; Elisabeth Haggård-Ljungquist; Klas Flärdh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacterial viruses; Bacteriophage; Phage; Phage therapy; multi-resistant bacteria; Klebsiella pneumoniae; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The global increase in antibiotic resistance levels in bacteria is a growing concern to our society and highlights the need for alternative strategies to combat bacterial infections. Bacterial viruses (phages) are the natural predators of bacteria and are as diverse as their hosts, but our understanding of them is limited. LÄS MER

  3. 3. The efficacy of bacterial viruses against multi-resistant Escherichia coli: from isolation to pharmacology

    Författare :Mohammadali Khan Mirzaei; Anders Nilsson; Rob Lavigne; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Phage therapy; Multiresistant E. coli; Pharmacodynamics; Pharmacokinetics; Bacterial viruses; Genomic; proteomic; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The increase of multi-resistant bacteria highlights that the golden era of antibiotics is ending and that alternative treatmentsare urgently needed. Phages have been historically used to treat bacterial infections prior to the discovery of antibiotics and have gained renewed interest in the past decade. LÄS MER

  4. 4. Infection kinetics, phylogenetics, and host interactions of bacteriophages

    Författare :Shazeeda Koonjan; Anders S. Nilsson; Lone Brøndsted; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacteriophage biology; infection kinetics; phylogenetics; host interactions; phage therapy; phage ecology and evolution; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Bacteriophages, or as they are most commonly referred to as phages, are viruses which are capable of infecting bacteria. They are environmentally plenty, found everywhere from the ground we walk on to contributing to our microbiome. They are highly diverse, coming in various sizes, shapes, and genomic compositions. LÄS MER

  5. 5. Study of phages for phage therapy : An Escherichia coli experience

    Författare :Mohammadali Khan Mirzaei; Anders Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The world is rapidly moving toward a post-antibiotic era as effective antibiotics are becoming fewer. phage therapy is a potentially possible method for treating infectious diseases and counts as an alternative method for antibiotic therapy. LÄS MER