Avancerad sökning

Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Defense-peptides against mycobacteria

    Författare :Charlotte M A Linde; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antimicrobial peptides; NK-lysin; granulysin; PR-39; Mycobacterium;

    Sammanfattning : Several members of the genus Mycobacterium can cause serious infections in both man and animal. One of the world's most serious infectious diseases, tuberculosis, is caused by the pathogen Mycobacterium tuberculosis. Specific defense to tuberculosis/mycobacteriosis is dependent on the individual's ability to mount a proficient immune response. LÄS MER

  3. 2. Isolation and characterization of regulatory peptides and bioactive compounds

    Författare :Åke Norberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Isolation of peptides and other bioactive compounds is an important and often necessary step to get the total information about their structures. This is demonstrated by a number of different characterizations in this thesis. LÄS MER

  4. 3. Pharmaceutical and mutational interference with virulence of Salmonella enterica serovar typhimurium

    Författare :Aurel Negrea; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Within the species Salmonella enterica are a diverse range of bacteria that can cause illness in humans and many animals. Salmonellae are extremely versatile and can adapt to a variety of environments and hosts. Typhoid and paratyphoid fever, caused by human-restricted S. enterica serovars Typhi and Paratyphi are common in the developing world. LÄS MER

  5. 4. Bacterial Resistance to Antimicrobial Peptides : Rates, Mechanisms and Fitness Effects

    Författare :Maria Pränting; Dan Andersson; Ian Chopra; Uppsala universitet; []
    Nyckelord :antimicrobial peptides; antibiotic resistance; fitness cost; bacterial evolution; small colony variants; cyclotides; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Mikrobiologi; Microbiology;

    Sammanfattning : The rapid emergence of bacterial resistance to antibiotics has necessitated the development of alternative treatment strategies. Antimicrobial peptides (AMPs) are important immune system components that kill microbes rapidly and have broad activity-spectra, making them promising leads for new pharmaceuticals. LÄS MER

  7. 5. Isolation, structure and processing of bioactive peptides

    Författare :Valentina Bonetto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Amino acid sequences deduced from DNA sequences do not prove in which forms proteins, peptides and their processed products are present in the tissues. The products of a single gene may give rise to variants of peptides because of post-transcriptional or post-translational processing. LÄS MER