Sökning: "Mycobacterium"
Visar resultat 1 - 5 av 129 avhandlingar innehållade ordet Mycobacterium.
1. Comparative genomics of the genus Mycobacterium : Genome evolution, phylogeny and diversity
Sammanfattning : The genus Mycobacterium includes more than 190 species, and many cause severe diseases such as tuberculosis and leprosy. According to the "World Health Organization", in year 2019 alone, 10 million people developed TB, and 1.4 million died. LÄS MER
2. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes
Sammanfattning : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. LÄS MER
3. Fighting Tuberculosis – : Structural Studies of Three Mycobacterial Proteins
Sammanfattning : This thesis presents the cloning, purification, crystallization, and structural studies of two unknown proteins from Mycobacterium tuberculosis, and of an aminotransferase from Mycobacterium smegmatis. Structural knowledge of these proteins is of highest interest for structure-based drug design, which is one of the approaches that can be used in order to fight tuberculosis (TB). LÄS MER
4. Mycobacterium avium infections in children
Sammanfattning : Mycobacterium avium belongs to a group of over 130 species of non-tuberculous mycobacteria (NTM) or environmental mycobacteria. The subspecies Mycobacterium avium avium was originally described as the causative agent of bird tuberculosis, but was later found to cause disease also in humans. LÄS MER
5. Mycobacterium tuberculosis and HIV coinfection : Effects on innate immunity and strategies to boost the immune response
Sammanfattning : Tuberculosis (TB) still remains a big threat today, being the leading cause of death by a single infectious agent. The TB epidemic is fueled by HIV along with the increasing drug-resistance which prolongs the already long treatment duration and decreases the success rate for curing TB. LÄS MER