Sökning: "Ovarian follicle"

Visar resultat 16 - 20 av 43 avhandlingar innehållade orden Ovarian follicle.

  1. 16. Studies of phosphatidylinositol 3 kinase (PI3K) signaling pathway in mammalian ovarian follicle activation and development

    Författare :Singareddy Rajareddy; Kui Liu; Anneli Stavreus-Evers; Umeå universitet; []
    Nyckelord :oocyte; follicular development; P13K pathway; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : The intra-oocyte signaling pathways that control oocyte growth and early follicular development are largely unknown. The aim of this thesis was to investigate the regulation and functions of phosphatidylinositol 3 kinase (PI3K) pathway in the oocyte, focusing in the roles of Foxo3a, p27, and Pten (phosphatase and tensin homolog deleted on chromosome ten). LÄS MER

  3. 17. Human gonadotrophins for ovarian stimulation in infertility treatment

    Författare :Jonas Harlin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Infertility problems are present in 10 to 15 % of couples of fertile age. Ovulatory dysfunction, as a single cause, can be successfully treated and in-vitro fertilisation (IVF) can help a considerable number of couples, also when male problems are present. LÄS MER

  4. 18. Ovarian response to vascular and toxic insults in early life : focus on ovarian reserve and fertility preservation

    Författare :Valentina Pampanini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The ovarian reserve is defined as the number of eggs embodied in primordial follicles. Every woman is born with a fixed number of primordial follicles, which are formed during fetal development. Pathological events can affect the ovarian reserve both preand postnatally and cause a premature ovarian insufficiency (POI), i.e. LÄS MER

  5. 19. Human ovarian follicles and oocytes : collection, cryopreservation, culture and gene expression

    Författare :Pu Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ovarian follicle; oocyte; follicular aspirate; organ culture; cAMP; cGMP; cryopreservation; microarray; human gene expression; embryonic stem cell; preimplantation;

    Sammanfattning : Infertility affects approximately 15% of couples globally. The most effective treatment today is in vitro fertilization. However, not all couples can be helped with the current techniques. To achieve better success, techniques of storage and in vitro maturation of ovarian follicles have to be improved. LÄS MER

  7. 20. Data analysis for discovering the protein profile dynamics of the human ovarian follicular fluid and BRAF mutated metastatic melanoma tissue. : -

    Författare :Indira Pla Parada; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; data analysis; malignant melanoma; ovarian follicular fluid; reproduction; bioinformatics; mass spectromery; female infertility;

    Sammanfattning : Proteomics is widely utilized to understand the function of cellular processes at the molecular level. Using liquid chromatography interfaced with mass spectrometry (LC-MS)-based proteomics, thousands of proteins can be identified and quantified in a single experiment and their relationship and interactions can be analyzed. LÄS MER