Sökning: "Ocular tissues"

Visar resultat 11 - 14 av 14 avhandlingar innehållade orden Ocular tissues.

  1. 11. The molecular biology of retinoid metabolism : identification of an 11-cis retinol dehydrogenase in the retinal pigment epithelium

    Författare :András Simon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :11-cis retinol; 11-cis retinol dehydrogenase; chromophore; 11-cis retinaldehyde; 9-cis retinol; 9-cis retinol dehydrogenase; retinal pigment epithelium; vitamin A; short-chain alcohol dehydrogenase;

    Sammanfattning : Vitamin A derivatives (retinoids) are essential molecules in the course of embryonic development, postnatal growth and adult physiology. The physiological functions of retinoids are thought to be mediated mainly by retinoic acid which regulates the expression of various genes, and 11-cis retinaldehyde, which is the common chromophore of visual pigments. LÄS MER

  3. 12. Damage mechanisms for near-infrared radiation induced cataract

    Författare :Zhaohua Yu; Per Söderberg; Konstantin Galichanin; Masami Kojima; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; infrared radiation; photochemical; thermal; forward light scattering; lens; cataract; temperature; Arrhenius equation; heat diffusion;

    Sammanfattning : Purpose: 1) To estimate the threshold dose and the time evolution for cataract induction by near infrared radiation (IRR) in seconds exposure time domain; 2) to determine the ocular temperature development during the threshold exposure; 3) to investigate if near IRR induces cumulative lens damage considering irradiance exposure time reciprocity; 4) to experimentally estimate the temperature in the lens indirectly from the measurement of temperature-induced light scattering increase.Methods: Before exposure, 6-weeks-old albino rats were anesthetized and the pupils of both eyes were dilated. LÄS MER

  4. 13. Laminins and alpha11 integrin in the human eye : importance in development and disease

    Författare :Berit Byström; Fatima Pedrosa Domellöf; Ulf Stenevi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; basement membranes; extracellular matrix; laminin; integrin; cornea; development; keratoconus; wound healing; remodeling; immunohistochemistry; Ophtalmiatrics; Oftalmiatrik;

    Sammanfattning : The extracellular matrix (ECM) offers a protective shelter for cells and provides signaling paths important for cell to cell communication. ECM consists of basement membranes (BM) and interstitial matrix. BMs provide mechanical support for parenchymal cells, influence cell proliferation, survival, migration and differentiation. LÄS MER

  5. 14. Characterization of secretory mechanisms in lacrimal and salivary glands

    Författare :Martin Dankis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dry mouth; dry eyes; antidepressant; muscarinic; purinergic; salivary secretion; tear secretion; lacrimal gland; in vivo; primary culture; co-culture; acinar; myoepithelial;

    Sammanfattning : Dry mouth and dry eyes are multifactorial morbidities that can lead to a severely reduced quality of life. Approximately 20% of the population suffers from ocular or oral dryness. LÄS MER