Sökning: "NSCLC"

Visar resultat 16 - 20 av 46 avhandlingar innehållade ordet NSCLC.

  1. 16. Apoptotic signaling in lung carcinoma cells : with focus on mechanisms of radioresistance

    Författare :Jessica Ekedahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In this thesis, IR-induced apoptotic signaling was studied in a panel of lung carcinoma cell lines. The goal was not only to achieve a better understanding of the process, but also to identify possible targets for pharmacological modulation to enhance the efficiency of radiotherapy. LÄS MER

  3. 17. Genomic characterization of non-small cell lung cancer - clinical and molecular implications

    Författare :Anna F Karlsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung cancer; histology; non-small cell lung cancer; gene expression; gene fusion; Methylation;

    Sammanfattning : Lung cancer accounts for 1.6 million cancers annually and 1.3 million deaths per year make the disease the deadliest type of cancer. Smoking is the most prominent cause. LÄS MER

  4. 18. Signalomics : unsupervised and global strategies to explore mechanisms of radioresistence in lung cancer cells

    Författare :Sara Ståhl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : To combat lung cancer (LC) which is the number one cancer associated killer, a combination of surgery, chemotherapy, radiotherapy and targeted agents are currently used. The main subtype of LC, Non small cell lung cancer (NSCLC) unfortunately responds poorly to conventional radiotherapy (RT) for reasons yet only partly understood. LÄS MER

  5. 19. Spatial immune analyses in clinical cancer tissue

    Författare :Max Backman; Patrick Micke; Fredrik Pontén; Johan Botling; Kurt Schalper; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immune landscape; non-small cell lung cancer; immune cells; multiplex immunofluorescence; spatial analysis; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Cancer is a leading cause of premature death and lung cancer is the deadliest cancer type, with non-small cell lung cancer (NSCLC) representing 85% of lung cancer cases. Despite promising development in cancer treatment in recent decades, overall prognosis is poor. LÄS MER

  7. 20. Real-world outcomes in oncology : assessing the value of rewardable innovation

    Författare :Nahila Justo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Recent years have seen a remarkable expansion of therapeutic options available for many forms of cancer. Evidence for the efficacy of these treatments have mainly come from randomized controlled trials, however questions often remain regarding the actual use, effectiveness and value of innovative therapies when used under the circumstances of routine clinical practice. LÄS MER