Sökning: "immune landscape"
Visar resultat 1 - 5 av 41 avhandlingar innehållade orden immune landscape.
1. Spatial immune analyses in clinical cancer tissue
Sammanfattning : Cancer is a leading cause of premature death and lung cancer is the deadliest cancer type, with non-small cell lung cancer (NSCLC) representing 85% of lung cancer cases. Despite promising development in cancer treatment in recent decades, overall prognosis is poor. LÄS MER
2. Mutation and immune profiling of non-small cell lung cancer
Sammanfattning : Several novel therapies that target molecular alterations and immune checkpoints in lung cancer have been introduced in the last decade. Still, only a minority of patients obtain long term disease control and overall survival remains poor. LÄS MER
3. Exploring the Molecular Landscape of Cutaneous Melanoma
Sammanfattning : Cutaneous malignant melanoma (CMM) is one of the most aggressive skin malignancies with poor prognosisfor the patients with metastatic disease. Earlier studies have highlighted the existing molecular diversityamongst CMM tumors. LÄS MER
4. Mapping the immune landscape in solid tumors : implications for immunotherapy
Sammanfattning : Our cells are programmed with various safety mechanisms to avoid transformation into tumor cells. In case these fail, we have a guarding immune system ready to recognize and eliminate these cells. Despite these safety measurements, cancer is one of the leading causes of death worldwide. The tumor cells find ways to escape the immune system. LÄS MER
5. The leukocyte complexity and mutational landscape of periampullary adenocarcinoma. Morphology matters
Sammanfattning : Background: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. LÄS MER