Sökning: "Mural cells"

Visar resultat 6 - 10 av 19 avhandlingar innehållade orden Mural cells.

  1. 6. Cdc42, orchestrator of vascular morphogenesis in the retina

    Författare :Alberto Álvarez-Aznar; Konstantin Gängel; Christer Betsholtz; Taija Mäkinen; Ondine Cleaver; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cdc42; endothelial cell; pericyte; mural cell; angiogenesis; CreERT2; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Cdc42 is a small GTPase that controls many cellular functions related to cytoskeletal dynamics, such as migration, polarity, and proliferation. Despite what we know of Cdc42 in other cell types, not much research has been done on the vasculature. LÄS MER

  3. 7. Tumor angiogenesis. Regulation of mural cell recruitment and endothelial sprouting

    Författare :Alexandra Abramsson; Göteborgs universitet; []
    Nyckelord :Angiogenesis; tumor; retina; PDGF; VEGF; platelet-derived growth factor; guidance; vascular endothelial growth factor.;

    Sammanfattning : The formation of new blood vessels is an inherent part of many physiological and pathological processes. Currently, there is a strong hope pathological situations like stroke, diabetic retinopathy and cancer may be affected by pharmacological regulators of blood vessel formation. LÄS MER

  4. 8. Endothelial : mural cell interplay in regulation of blood- and lymph vessel development and function

    Författare :Yixin Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Blood- and lymphatic vascular development and homeostasis depend on correct endothelial- mural cell interaction, and dysregulation thereof is apparent in multiple human diseases. However the mechanisms controlling the formation of these respective vascular systems are not fully understood. LÄS MER

  5. 9. Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

    Författare :Johan Heldin; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; cell migration; signaling; VEGF; FGD5; ExoC3L2; microRNA; RhoD; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Blood vessels deliver nutrients and oxygen to tissues. Importantly, the functions and growth of blood vessels are commonly altered in disease. The inside of all blood vessels are lined with endothelium, a thin specialized layer of endothelial cells that separate the blood from other tissues. LÄS MER

  7. 10. On angiogenesis modulation

    Författare :Mattias Kalén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During evolution, the transition from unicellular to multicellular organisms required the origin of a transport system capable of interconnecting specialized cells throughout the body of the organism. In higher animals, this route of transportation is the cardiovascular system, which allows gas exchange, and transport of immune cells, hormones, macromolecules, nutrients and waste products. LÄS MER