Sökning: "Mural cells"
Visar resultat 11 - 15 av 19 avhandlingar innehållade orden Mural cells.
11. Studies on pericytes in health and disease
Sammanfattning : Pericytes are the perivascular mural cells of microvessels. They are intimately associated with endothelial cells and communicate with them via direct physical contact or through paracrine signaling pathways. These interactions are important for blood vessel maturation, remodeling, and maintenance. LÄS MER
12. Exploring the functional heterogeneity of the tumor microenvironment
Sammanfattning : Tumors are complex entities, composed of different functional populations of malignant and stromal cells. There is an emerging importance to understand previously unmapped communication routes between different cell and non-cell compartments of the tumor microenvironment. LÄS MER
13. Biological activities of novel platelet-derived growth factors, PDGF-C and PDGF-D
Sammanfattning : Platelet-derived growth factors (PDGFs) belong to the PDGF/VEGF (vascular endothelial growth factor) family of growth factors. Members of this family share a common structural feature, a conserved PDGF/VEGF homology domain, containing eight invariant cysteine residues. LÄS MER
14. The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis
Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones through creation of new vessel branch points by sprouting or vessel splitting, is an important part of tissue growth in both physiological processes like wound healing and pathological conditions such as cancer. Growth factors like VEGF-A, FGF-2 and PDGF-BB are involved in both types of angiogenesis. LÄS MER
15. Vascular remodeling in pulmonary hypertension
Sammanfattning : Pulmonary hypertension (PH) is a progressive obliterative vasculopathy with multifactorial etiology and high mortality rate. Endothelial dysfunction, excessive vascular remodeling, inflammation and in situ thrombosis contribute to increased vascular resistance and gradual occlusion of pulmonary vessels. LÄS MER