Sökning: "LIGANDS"

Visar resultat 21 - 25 av 934 avhandlingar innehållade ordet LIGANDS.

1. 21. Versatile ligands for selective metal catalysis

   Författare :Magnus Cernerud; KTH; []
   Nyckelord :;

   Sammanfattning : .... LÄS MER

3. 22. Interleukin-1 Receptors and their Ligands

   Författare :David Malinowsky; Gordon W Duff; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

   Sammanfattning : Interleukin-1 (IL-1) is an endogenous mediator of the inflammatory response. IL-1 executes its actions by binding and subsequent activation of the IL-1 receptor (IL-1R) proteins. Among the many systemic effects of IL-1, the fever response was the first to be investigated. LÄS MER

4. 23. Equilibrium studies of ternary aluminium(III) hydroxo complexes with ligands related to conditions in natural waters

   Författare :Lars-Olof Öhman; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aqueous solution; binary and ternary hydroxo complexes of Al3 ; carbonic acid; citric acid; phenolic ligands; emf-titrations; equilibrium analysis; model calculations towards natural waters;

   Sammanfattning : The thesis is a summary and discussion of eight papers. During the last decades, precipitation has become increasingly acidic due to the extensive use of fossil fuels. In areas of poorly buffered bedrocks, e.g. LÄS MER

5. 24. Molecular 3D networks : self assembly of metal ions with bis-chelating ligands

   Författare :Krister Larsson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; hydrogen bonding; networks; chirality; coordination chemistry; bis-chelating ligands; pi-pi-interactions; single crystal X-ray diffraction;

   Sammanfattning : .... LÄS MER

7. 25. Discovery of Novel Macrocyclic Ligands for Difficult Targets : Applications to Natural Product Derived Keap1 Inhibitors

   Författare :Fabio Begnini; Jan Kihlberg; Anders Bach; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Macrocycles; Keap1-Nrf2; Protein-protein interactions; Natural products;

   Sammanfattning : The development of small-molecule ligands for biological targets that possess large, featureless or highly polar binding sites is a challenging task. This thesis is focused on a novel lead generation strategy to identify macrocyclic ligands for difficult-to-drug targets, as well as on the relationship between cell permeability and the conformations of macrocycles. LÄS MER