Sökning: "Karen Briley Saebo"

Hittade 1 avhandling innehållade orden Karen Briley Saebo.

1. 1. Degradation, Metabolism and Relaxation Properties of Iron Oxide Particles for Magnetic Resonance Imaging

   Författare :Karen Briley Saebo; Håkan Ahlström; Atle Bjørnerud; Michael Knopp; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; Magnetic Resonance Imaging; contrast agents; iron oxide particles; metabolism; relaxation mechanisms; Radiologisk forskning; Radiological research; Radiologisk forskning;

   Sammanfattning : Whereas the effect of size and coating material on the pharmacokinetics and biodistribution of iron oxide based contrast agents are well documented, the effect of these parameters on liver metabolism has never been investigated. The primary purpose of this work was to evaluate the effect of iron oxide particle size and coating on the rate of liver clearance and particle degradation using a rat model. LÄS MER