Sökning: "Atle Bjørnerud"

Hittade 4 avhandlingar innehållade orden Atle Bjørnerud.

1. 1. Proton Relaxation Properties of a Particulate Iron Oxide MR Contrast Agent in Different Tissue Systems : Implications for Imaging

   Författare :Atle Bjørnerud; Graham A. Wright; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Iron oxide nanoparticles; USPIO; NC100150 Injection; water exchange limited relaxation; MR perfusion imaging.; Onkologi; Oncology; Onkologi; radiologi; Radiology;

   Sammanfattning : Knowledge of the relationship between in vivo contrast agent concentration and magnetic resonance (MR) signal response is an important requirement in contrast enhanced MR imaging in general and in MR based perfusion imaging in particular. This relationship is a complex function of the properties of the contrast agent as well as the structure of the target tissue. LÄS MER

3. 2. Degradation, Metabolism and Relaxation Properties of Iron Oxide Particles for Magnetic Resonance Imaging

   Författare :Karen Briley Saebo; Håkan Ahlström; Atle Bjørnerud; Michael Knopp; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; Magnetic Resonance Imaging; contrast agents; iron oxide particles; metabolism; relaxation mechanisms; Radiologisk forskning; Radiological research; Radiologisk forskning;

   Sammanfattning : Whereas the effect of size and coating material on the pharmacokinetics and biodistribution of iron oxide based contrast agents are well documented, the effect of these parameters on liver metabolism has never been investigated. The primary purpose of this work was to evaluate the effect of iron oxide particle size and coating on the rate of liver clearance and particle degradation using a rat model. LÄS MER

4. 3. Perfusion measurements by dynamic susceptibility MRI

   Författare :Arvid Morell; Atle Bjørnerud; Håkan Ahlström; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diagnostic radiology; Diagnostisk radiologi; Radiology; Radiologi;

   Sammanfattning : .... LÄS MER

5. 4. Quantitative Tracer Based MRI Perfusion : Potentials and Limitations

   Författare :Arvid Morell; Atle Bjørnerud; Håkan Ahlström; Linda Knutsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; Perfusion; Contrast agent; Relaxivity; Radiology; Radiologi;

   Sammanfattning : Tracer based MRI perfusion measurements is a clinically useful tool to assess regional distributions of tissue blood flow and volume. The method may be based on any of the three relaxation mechanisms T1, T1 and T2*, the latter denoted DSC-MRI being the most common. LÄS MER