Sökning: "Johannes De Vries"

Hittade 2 avhandlingar innehållade orden Johannes De Vries.

  1. 1. Studies on Metalloenzymatic Dynamic Kinetic Resolutions and Iron-Catalyzed Reactions of Allenes

    Författare :Karl P. J. Gustafson; Jan-Erling Bäckvall; Johannes de Vries; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Racemization; Dynamic Kinetic Resolution; Enzyme Catalysis; XAS; Asymmetric Synthesis; organisk kemi; Organic Chemistry;

    Sammanfattning : The main focus of this thesis lies in the development of new transition metal-catalyzed chemoenzymatic dynamic kinetic resolutions (DKR) of both alcohols and amines. The first part of the thesis deals with the development of new heterogeneous systems for the DKR of amines. LÄS MER

  3. 2. Transition metal- and lipase-catalyzed reactions : Dynamic resolutions, hydrogen transfer and enzyme engineering

    Författare :Patrik Krumlinde; Jan-Erling Bäckvall; Johannes G. de Vries; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dynamic kinetic resolution; dynamic kinetic asymmetric transformation; hydrogen transfer; directed evolution; enzyme engineering; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis mainly focuses on chemoenzymatic processes and can be divided into three parts: The first part of the thesis, chapters 2-4, is devoted to the development of combined ruthenium- and enzyme-catalyzed dynamic processes. In these processes the metal catalyst racemizes (epimerizes) the alcohol substrate via hydrogen transfer and the enzyme transforms the substrate into enantiomerically enriched product. LÄS MER