Sökning: "Intrathecal administration"

Visar resultat 16 - 19 av 19 avhandlingar innehållade orden Intrathecal administration.

  1. 16. Neurogenesis, neural stem cells and nitric oxide in neuroinflammation

    Författare :Alexandre I Danilov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurogenesis; neuronal stem cells; nitric oxide; Multiple Sclerosis; EAE; brain trauma;

    Sammanfattning : We investigated whether nitric oxide (NO) is produced in MS patients, determining the concentrations of its oxidation products (NOx) in CSF. The total levels of NOx in CSF were significantly increased in all MS groups as compared to healthy controls and tension headache patients. LÄS MER

  3. 17. Perioperative regimens for patients undergoing elective hip or knee arthroplasties

    Författare :Andreas Harsten; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthetic techniques; dietary carbohydrates; length of hospital stay; total knee arthroplasty; total hip arthroplasty;

    Sammanfattning : Background: Elective knee and hip arthroplasty are common surgical procedures. Improved anaesthetic and nutritional care has the potential of increasing patient satisfaction and reducing length of hospital stay (LOS). LÄS MER

  4. 18. Inflammatogenic properties of endogenous DNA

    Författare :Shahin Hajizadeh; Göteborgs universitet; []
    Nyckelord :Inflammation; mtDNA; oxidized DNA; SF; CSF; RA; dementia;

    Sammanfattning : Bacterial DNA and CpG-containing oligodeoxynucleotides (ODNs) induce host inflammatory responses as a result of their content of unmethylated ¡§CpG motifs¡¨. Since the CpG motifs in the mitochondrial (mt) genome are in this respect similar to bacterial DNA, in that they are non-methylated, we investigated whether mtDNA also displays inflammatogenic potential. LÄS MER

  5. 19. The role of neuropeptides in spinal nociceptive mechanisms with special emphasis on galanin, neuropeptide Y and orphanin FQ/nociceptin

    Författare :Isabella Shi Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :analgesia; antinociception; flexor reflex; galanin; galanin message-associated peptide GMAP ; neuropeptide Y NPY ; nociceptin; nociception; nocistatin; orphanin FQ; pain;

    Sammanfattning : Several peptides present in sensory neurons and in the spinal cord have been recognized to have inhibitory action in nociception. In this thesis, we have used the flexor reflex preparation in rats to study the role of several proposed inhibitory neuropeptides, galanin, galanin message-associated peptide (GMAP), neuropeptide Y (NPY), orphanin FQ and nocistatin in spinal nociceptive processing under normal conditions, after inflammation or peripheral nerve injury. LÄS MER