Sökning: "Shahin Hajizadeh"

Hittade 1 avhandling innehållade orden Shahin Hajizadeh.

1. 1. Inflammatogenic properties of endogenous DNA

   Författare :Shahin Hajizadeh; Göteborgs universitet; []
   Nyckelord :Inflammation; mtDNA; oxidized DNA; SF; CSF; RA; dementia;

   Sammanfattning : Bacterial DNA and CpG-containing oligodeoxynucleotides (ODNs) induce host inflammatory responses as a result of their content of unmethylated ¡§CpG motifs¡¨. Since the CpG motifs in the mitochondrial (mt) genome are in this respect similar to bacterial DNA, in that they are non-methylated, we investigated whether mtDNA also displays inflammatogenic potential. LÄS MER