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Visar resultat 11 - 15 av 100 avhandlingar som matchar ovanstående sökkriterier.
11. Novel Culture Strategies and Signal Transduction Pathways of Pluripotent Stem Cells
Sammanfattning : Pluripotent stem cells (PSCs) can self-renew indefinitely in culture while maintaining their capacity to differentiate into any cell type of an organism, thus offering novel sources for drug screening, in vitro disease modelling, and cell replacement therapies. However, due to their sensitive nature, many PSC lines are still cultured using undefined components such as serum or serum-derived components, on either feeder cells or complex protein mixes such as Matrigel or gelatine. LÄS MER
12. Human pluripotent stem cells : effects of handling and microenvironment
Sammanfattning : Pluripotent stem cells hold great promise in regenerative medicine and drug development due to their developmental potential towards multiple lineages. However, there are still hurdles to overcome before these cells are safe enough for clinical use even though attempts have already been initiated. LÄS MER
13. Transcriptional profiling of human embryonic stem cells and their functional derivatives
Sammanfattning : Human embryonic stem cells (hESCs) represent populations of pluripotent, undifferentiated cells with unlimited replication capacity, and with the ability to differentiate into any functional cell type in the human body. Based on these properties, hESCs and their derivatives provide unique model systems for basic research on embryonic development. LÄS MER
14. Derivation, Characterization and Differentiation of Feeder-Free Human Embryonic Stem Cells
Sammanfattning : Human embryonic stem cells (hESCs) are pluripotent cells with self-renewal ability, derived from the inner cell mass of a human blastocyst. They have the remarkable potential to develop into different cell types and can thus be used to regenerate and restore damaged tissues and organs in the entire body. LÄS MER
15. Modeling human germ cell development with pluripotent stem cells and characterizing the putative oogonial stem cells
Sammanfattning : The current understanding of human germ cell development is limited and is at most parts extrapolated from studies of mice or other model organisms. Particularly, the specification events of human germ cell lineage are largely unknown, which is at least in part due to inaccessibility of early stages of human development. LÄS MER