Sökning: "Human Protein Project"

Visar resultat 11 - 15 av 143 avhandlingar innehållade orden Human Protein Project.

1. 11. Initiation of Protein Biosynthesis in Skeletal Muscles at Feeding

   Författare :Britt-Marie Iresjö; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein synthesis; Translation initiation; amino acids; Snat 2; MHC2A; IGF-I;

   Sammanfattning : Background and aim. Artificial nutrition by intravenous feeding has for decades indicated less than optimal support of whole-body protein metabolism and balance during some treatment conditions. LÄS MER

3. 12. Characterization of Antigenic Properties and High Throughput Protein Purification

   Författare :Johanna Steen; Sophia Hober; Mats Ohlin; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high throughput; protein purification; sample preparation; antigen solubility; immunogenicity; epitope mapping; antigen design; Bioengineering; Bioteknik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Sammanfattning : To understand the cellular processes, knowledge of the localization and function of proteins are essential. There are several high throughput ventures examining the human proteome. However, there are some bottlenecks in these ventures. For example the production and expression of soluble proteins for analysis. LÄS MER

4. 13. Selection of antigens for antibody-based proteomics

   Författare :Lisa Berglund; Mathias Uhlén; Sören Brunak; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; epitope; antigen; antibody; affinity; protein; proteome; proteomics; bioinformatics; prediction; primer design; sequence similarity; Bioengineering; Bioteknik;

   Sammanfattning : The human genome is predicted to contain ~20,500 protein-coding genes. The encoded proteins are the key players in the body, but the functions and localizations of most proteins are still unknown. LÄS MER

5. 14. Analysis of proteins related toautoimmune and inflammatorydiseases with focus on newenrichment methodologies and MALDI-TOF MS

   Författare :Yuye Zhou; Åsa Emmer; Margret Thorsteinsdottir; KTH; []
   Nyckelord :Protein; Glycopeptide; IgG; Osteopontin; Enrichment; Digestion; Separation; Microchip; MALDI-TOF MS; Kemi; Chemistry;

   Sammanfattning : Proteins have been widely studied in biological sample analysis due to the association with diseases. In the present project, method and technique development was carried out on the analysis of two proteins, immunoglobulin G (IgG) and osteopontin (OPN). LÄS MER

7. 15. Biochemical properties of human glutaredoxins

   Författare :Catrine Johansson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Glutaredoxins (Grxs) are highly conserved thiol-disulfide oxidoreductases that utilize electrons from the tripeptide glutathione (GSH) to catalyze thiol-disulfide exchange reactions. Bacteria, yeast and plants contain multiple dithiol Grxs, which are involved in different cellular processes like DNA synthesis, defense against oxidative stress, apoptosis, and regulation of transcription factor binding activity. LÄS MER